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Inflammatory and oxidative stress biomarkers in allergic rhinitis: the effect of smoking
(2009)
Accumulating evidence confirms the presence of pan-airway inflammation in allergic rhinitis patients. Smoking is known to affect the asthmatic airway inflammation. However, no study has evaluated the impact of smoking on ...
Phenotypic mismatch repair hMSH2 and hMLH1 gene expression profiles in primary non-small cell lung carcinomas
(2009)
Background: Defects in the human DNA mismatch repair genes (MMR) hMSH2 and hMLH1 arc responsible for the development of sporadic and hereditary colorectal cancers. The role of MMR genes in the pathogenesis of lung cancer ...
Clinical, functional and biochemical changes during recovery from COPD exacerbations
(2009)
The pathways underlying chronic obstructive pulmonary disease exacerbations (ECOPD) remain unclear. This study describes the clinical., functional and biochemical changes during recovery from ECOPD. Thirty hospitalized ...
Global assessment of the COPD patient: Time to look beyond FEV1?
(2009)
COPD is a diverse disease entity with multiple dimensions that uniquely define the patient's performance, morbidity and mortality. FEV1 is both the traditional metric used to define the progression of COPD as well as the ...
Serum VEGF levels are related to the presence of pulmonary arterial hypertension in systemic sclerosis
(2009)
Background: The association between systemic sclerosis and pulmonary arterial hypertension (PAH) is well recognized. Vascular endothelial growth factor (VEGF) has been reported to play an important role in pulmonary ...
Pleural electrophysiology variations according to location in pleural cavity
(2009)
The aim of the study was to compare the electrophysiology profile of sheep pleura originated from different locations of the pleural cavity with the respective profile in humans. Sheep specimens obtained from upper and ...
Matrix Metalloproteinases in Respiratory Diseases: From Pathogenesis to Potential Clinical Implications
(2009)
Matrix metalloproteinases (MMPs) are zinc-endopeptidases responsible for degradation of the extracellular matrix (ECM) components including basement membrane collagen, interstitial collagen, fibronectin, and various ...
Anti-survivin antibody responses in lung cancer
(2009)
Existing evidence regarding spontaneous anti-survivin humoral responses in lung cancer is inconclusive. Moreover, despite that cancer cell death elicited by radiotherapy and some chemotherapeutic agents seems to be ...