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The acute effect of smoking in healthy and asthmatic smokers
(2010)
Background Acute exposure to cigarette smoke is related to airway and systemic inflammation and oxidative stress. Little is known about the acute effect of cigarette smoking in smoking asthmatics. The aim of this study was ...
Systemic and airway inflammation and the presence of emphysema in patients with COPD
(2010)
The aim of this study was to determine the impact of HRCT-confirmed emphysema on biomarkers evaluating airway and systemic inflammation in COPD patients. Forty-nine consecutive male COPD outpatients with stable COPD were ...
Matrix Metalloproteinases in Respiratory Diseases: From Pathogenesis to Potential Clinical Implications
(2009)
Matrix metalloproteinases (MMPs) are zinc-endopeptidases responsible for degradation of the extracellular matrix (ECM) components including basement membrane collagen, interstitial collagen, fibronectin, and various ...