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The Catabolic Role of Toll-Like Receptor 2 (TLR-2) Mediated by the NF-kappa B Pathway in Septic Arthritis
(2011)
Toll-like receptors (TLRs) are involved in mediating cell activation on stimulation with microbial components. Our objective was to investigate the role of 'PLR-2 mediated by the NF-kappa B pathway in septic arthritic ...
Do steroids, conventional non-steroidal anti-inflammatory drugs and selective Cox-2 inhibitors adversely affect fracture healing?
(2009)
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used drugs worldwide. They are prescribed for orthopaedic conditions such as osteoarthritis, soft-tissue injuries and fractures. The new generation ...
Protective Effect of Atorvastatin in Cultured Osteoarthritic Chondrocytes
(2010)
The aim of our study was to evaluate the in vitro effect of an HMG-CoA reductase inhibitor, atorvastatin, on the expression of significant anabolic and catabolic genes in human osteoarthritic chondrocytes and to explore ...
Influence of Interleukin 1 alpha (IL-1 alpha), IL-4, and IL-6 Polymorphisms on Genetic Susceptibility to Chronic Osteomyelitis
(2008)
The association between cytokine gene polymorphisms and chronic osteomyelitis was investigated in order to determine whether genetic variability in cytokine genes predisposes to osteomyelitis susceptibility. Significant ...
Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis
(2012)
Background: Recent studies have implied that osteoarthritis (OA) is a metabolic disease linked to deregulation of genes involved in lipid metabolism and cholesterol efflux. Sterol Regulatory Element Binding Proteins (SREBPs) ...
Total knee replacement performed with either a mini-midvastus or a standard approach - A prospective randomised clinical and radiological trial
(2008)
We report the clinical and radiological results of a two-to three-year prospective randomised study which was designed to compare a minimally-invasive technique with a standard technique in total knee replacement and was ...
The effects of the short-term administration of low therapeutic doses of anti-COX-2 agents on the healing of fractures - An experimental study in rabbits
(2007)
We have evaluated the effect of the short-term administration of low therapeutic doses of modern COX-2 inhibitors on the healing of fractures. A total of 40 adult male New Zealand rabbits were divided into five groups. A ...
Clinical and epidemiological features of upper-extremity infections caused by Staphylococcus aureus carrying the PVL gene: A four-year study in Greece
(2008)
Background: All Staphyloccus aureus isolated during 2003-2006 at a university hospital in Thessalia, central Greece, from ulcerative upper-extremity infection were tested for the presence of PVL gene and for possible clonal ...
Complex regional pain syndrome type I as a consequence of trauma or surgery to upper extremity: management with intravenous regional anaesthesia, using lidocaine and methyloprednisolone
(2011)
Complex regional pain syndrome type I (CRPS-I) is a known complication after surgery or trauma to the upper extremity and is difficult to treat. A simple and easily tolerated method of treatment that includes intravenous ...