Recherche
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Synthesis and biological evaluation of potential small molecule inhibitors of tumor necrosis factor
(2015)
Inhibition of tumor necrosis factor (TNF) production or function by small molecules has become a major focus in the pharmaceutical industry for the treatment of rheumatoid arthritis. In this study, a series of 39 novel ...
Duplex Real-time PCR assay and SYBR green I melting curve analysis for molecular identification of HPV genotypes 16, 18, 31, 35, 51 and 66
(2015)
Long-term infection with high-risk HPV genotypes is the leading cause of cervical cancer. In the present study a Duplex Real-time PCR assay was developed in order to identify HPV types 16, 18, 31, 35, 51 and 66 in three ...
DIANA-TarBase v7.0: indexing more than half a million experimentally supported miRNA:mRNA interactions
(2015)
microRNAs (miRNAs) are short non-coding RNA species, which act as potent gene expression regulators. Accurate identification of miRNA targets is crucial to understanding their function. Currently, hundreds of thousands of ...
DIANA-miRPath v3.0: deciphering microRNA function with experimental support
(2015)
The functional characterization of miRNAs is still an open challenge. Here, we present DIANA-miRPath v3.0 (http://www.microrna.gr/miRPathv3) an online software suite dedicated to the assessment of miRNA regulatory roles ...
RNAcentral: an international database of ncRNA sequences
(2015)
The field of non-coding RNA biology has been hampered by the lack of availability of a comprehensive, up-to-date collection of accessioned RNA sequences. Here we present the first release of RNAcentral, a database that ...
Effect of dietary incorporation of a multi-strain probiotic on growth performance and health status in rainbow trout (Oncorhynchus mykiss)
(2015)
Dietary supplementation with a multi-strain probiotic containing Bacillus subtilis, Enterococcus faecium, Pediococcus acidilactici and Lactobacillus reuteri has been examined for its effects on growth performance, intestinal ...
Application of a new oxidation-reduction potential assessment method in strenuous exercise-induced oxidative stress
(2015)
Objectives: The aim of the study was to test a novel method for assessing oxidative stress, the RedoxSYS (TM) diagnostic system, a holistic, fast, minimally invasive, and requiring small sample volume method, that measures ...
Gilthead seabream (Sparus aurata) response to three music stimuli (Mozart-"Eine Kleine Nachtmusik," Anonymous-"Romanza," Bach-"Violin Concerto No. 1") and white noise under recirculating water conditions
(2015)
This study presents the results of the response of Sparus aurata to three different musical stimuli, derived from the transmission (4 h per day, 5 days per week) of particular music pieces by Mozart, Romanza and Bach (140 ...
Inter-comparison of the potentially active prokaryotic communities in the halocline sediments of Mediterranean deep-sea hypersaline basins
(2015)
The sediment microbiota of the Mediterranean deep-sea anoxic hypersaline basins (DHABs) are understudied relative to communities in the brines and halocline waters. In this study, the active fraction of the prokaryotic ...
Oxidative stress and antioxidant status in patients with autoimmune liver diseases
(2015)
Objective: To estimate oxidative stress and antioxidant components during different stages of autoimmune liver diseases and assess their possible implication on disease progression. Methods: We determined several markers ...