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Increased Plasma Angiogenin Level is Associated and May Contribute to Decreased T-Cell Zeta-Chain Expression in Hemodialysis Patients
(2013)
Hemodialysis (HD) patients are characterized by impaired T-cell function at least in part because of T-cell zeta-chain downregulation due to inflammation. Angiogenin responds as an acute phase reactant, is increased in HD ...
Plasma Angiogenin and Vascular Endothelial Growth Factor A Among Hemodialysis Patients
(2012)
Introduction. Angiogenesis plays a role in the pathogenesis of coronary heart disease (CHD) and diabetes mellitus (DM) pathology, and certain angiogenic factors are increased by inflammation. The aim of this study was to ...
Perilipin-1 in Hemodialyzed Patients: Association With History of Coronary Heart Disease and Lipid Profile
(2012)
Perilipin-1 surrounds lipid droplets in both adipocytes and in atheroma plaque foam cells and controls access of lipases to the lipid core. In hemodialysis (HD) patients, dyslipidemia, malnutrition, inflammation and ...
Plasma vascular endothelial growth factor and angiogenin are positively related to erythropoietin dose in hemodialysis patients
(2013)
Purpose: Experimental data confirmed that erythropoietin (EPO) administration alters the course of various pathological situations such as heart failure and tumor growth by inducing vascular endothelial growth factor-A ...
Lipopolysaccharide and hypoxia significantly alters interleukin-8 and macrophage chemoattractant protein-1 production by human fibroblasts but not fibrosis related factors
(2011)
Besides extracellular matrix production, fibroblasts are able to produce various cytokines. Their ubiquitous position makes fibroblasts appropriate cells for sensing various noxious stimuli and for attracting immune cells ...
Suppression of humoral immune response to hepatitis B surface antigen vaccine in BALB/c mice by 1-methyl-tryptophan co-administration
(2011)
Background and the purpose of the study: Indoleamine 2,3-dioxygenase (IDO) suppresses adaptive immune response. The purpose of this study was to determine the effect of the IDO inhibitor namely 1-methyl-DL-tryptophan ...
Inverse Association of Serum 25-Hydroxyvitamin D With Markers of Inflammation and Suppression of Osteoclastic Activity in Hemodialysis Patients
(2012)
Introduction. In hemodialysis patients, 25-hydroxyvitamin D conversion to active 1,25-dihydroxyvitamin D by the kidneys is very limited. The expression of both vitamin D receptor and 1 alpha-hydroxylase in cells of the ...
Arginase type I as a marker of coronary heart disease in hemodialysis patients
(2011)
Cardiovascular disease, and mainly coronary heart disease (CHD), is the leading cause of death in hemodialysis (HD) patients. Non-traditional risk factors may play an important role in this population. Arginase is known ...
Indoleamine 2,3-dioxygenase is increased in hemodialysis patients and affects immune response to hepatitis B vaccination
(2011)
Background: Acquired immunity is impaired in hemodialysis (HD) patients. Indoleamine 2,3-dioxygenase (IDO) is inducible by inflammation and through tryptophan depletion and generation of kynurenine pathway products suppresses ...