OBJECTIVE Pituitary responsiveness to GnRH varies throughout the normal menstrual cycle, We have investigated whether there are differences in the ovarian mechanisms which regulate gonadotrophin secretion between the ...

It has been reported that oestradiol may play a role in the production of leptin from adipocytes, To investigate this relationship further, nine normally ovulating women were studied during two menstrual cycles, i.e. an ...

Oestradiol enhances pituitary sensitivity to gonadotrophin-releasing hormone (GnRH) in normal women, while in women undergoing ovulation induction the putative factor gonadotrophin surge attenuating factor (GnSAF) attenuates ...

Superovulation induction in women attenuates the pituitary response to gonadotropin-releasing hormone (GnRH). The aim of this study was to assess the duration of the suppressing activity of the ovaries on the pituitary. ...

The suppression of the pituitary-gonadal axis by the administration of gonadotrophin-releasing hormone agonists (GnRH-a) is used occasionally as an adjunct therapy with gonadotrophins for ovulation induction in women with ...

Recent clinical studies have suggested that women with polycystic ovarian syndrome (PCOS) may have disturbances of growth hormone (GH) kinetics and the GH/insulin-like growth factor (IGF)-I system. The knowledge that in ...