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Endothelial Progenitor Cells in the Pathogenesis of Idiopathic Pulmonary Fibrosis: An Evolving Concept

Malli, F.; Koutsokera, A.; Paraskeva, E.; Zakynthinos, E.; Papagianni, M.; Makris, D.; Tsilioni, I.; Molyvdas, P. A.; Gourgoulianis, K. I.; Daniil, Z. (2013)

Background: Idiopathic pulmonary fibrosis (IPF) has been associated with abnormal vascular remodeling. Bone marrow derived endothelial progenitor cells (EPCs) are considered to possess lung tissue repair and vascular ...

Vascular endothelial growth factor (VEGF) in pleural effusions

Kiropoulos, T. S.; Daniil, Z.; Gourgoulianis, K. I.; Zakynthinos, E. (2007)

Pleural effusion is a common clinical problem in everyday clinical practice. Vascular endothelial growth factor (VEGF) is a 34-45 kDa homodimeric glycoprotein, which is a potent mediator of angiogenesis and vascular ...

Predicting Short-term Mortality in Patients With Pulmonary Embolism: A Simple Model

Papaioannou, A. I.; Kastanis, A.; Malli, F.; Zakynthinos, E.; Minas, M.; Mpakarozi, M.; Moka, S.; Zintzaras, E.; Gourgoulianis, K. I.; Daniil, Z. (2013)

Background: The aim of the present study was to develop a simple prognostic rule that could classify patients with pulmonary embolism (PE) into categories of increased risk of 30-day mortality. Methods: One hundred patients ...

Pulmonary arterial hypertension in a patient with common variable immunodeficiency and unilateral bronchiectasis: Successful treatment with iloprost

Daniil, Z.; Karetsi, E.; Zakynthinos, E.; Bakratsi, E.; Kalala, F.; Gourgoulianis, K. I. (2007)

The present study describes a case of severe pulmonary arterial hypertension (PAH) associated with unilateral lung destruction due to bronchiectasis in a patient with common variable immunodeficiency (CVID). Initially, the ...

Systemic and airway inflammation and the presence of emphysema in patients with COPD

Papaioannou, A. I.; Mazioti, A.; Kiropoulos, T.; Tsilioni, I.; Koutsokera, A.; Tanou, K.; Nikoulis, D. J.; Georgoulias, P.; Zakynthinos, E.; Gourgoulianis, K. I.; Kostikas, K. (2010)

The aim of this study was to determine the impact of HRCT-confirmed emphysema on biomarkers evaluating airway and systemic inflammation in COPD patients. Forty-nine consecutive male COPD outpatients with stable COPD were ...

Serum VEGF levels are related to the presence of pulmonary arterial hypertension in systemic sclerosis

Papaioannou, A. I.; Zakynthinos, E.; Kostikas, K.; Kiropoulos, T.; Koutsokera, A.; Ziogas, A.; Koutroumpas, A.; Sakkas, L.; Gourgoulianis, K. I.; Daniil, Z. D. (2009)

Background: The association between systemic sclerosis and pulmonary arterial hypertension (PAH) is well recognized. Vascular endothelial growth factor (VEGF) has been reported to play an important role in pulmonary ...