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Αποτελέσματα 9651-9660 από 19702
The dietary flavonoid kaempferol effectively inhibits HIF-1 activity and hepatoma cancer cell viability under hypoxic conditions
(2010)
Hepatocellular carcinoma (HCC) is characterized by high mortality rates and resistance to conventional treatment. HCC tumors usually develop local hypoxia, which stimulates proliferation of cancer cells and renders them ...
New Sequence Variants in HLA Class II/III Region Associated with Susceptibility to Knee Osteoarthritis Identified by Genome-Wide Association Study
(2010)
Osteoarthritis (OA) is a common disease that has a definite genetic component. Only a few OA susceptibility genes that have definite functional evidence and replication of association have been reported, however. Through ...
A new bifunctional tridentate NSN ligand leading to cationic tricarbonyl fac- M(NSN)(CO)(3) (+) (M = Re, Tc-99m) complexes
(2013)
The synthesis and characterization of the new NSN tridentate bifunctional chelating agent 3-[2-(2'-pyridin-2-yl-ethylsulfanyl)ethylamino] propionic acid (as its hydrochloric salt, 1) and of its corresponding rhenium comp ...
Preprocessing storage conditions for green 'Conservolea' and 'Chondrolia' table olives
(2002)
Green olives (Olea europaea L. cvs. 'Conservolea' and 'Chondrolia'), destined for Spanish-style processing, were harvested at the beginning and the end of commercial harvest period and stored at 5 and 7.5 degreesC in air ...
Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression
(2012)
Adaptation to hypoxia involves hypoxia-inducible transcription factors (HIFs) and requires reprogramming of cellular metabolism that is essential during both physiological and pathological processes. In contrast to the ...
Atypical CRM1-dependent nuclear export signal mediates regulation of hypoxia-inducible factor-1 alpha by MAPK
(2008)
Hypoxia-inducible factor 1 (HIF-1) is the key transcriptional activator of hypoxia-inducible genes and an important anti-cancer target. Its regulated subunit, HIF-1 alpha, is controlled by oxygen levels and major signaling ...
Rarefied gas flow in a triangular duct based on a boundary fitted lattice
(2008)
The rarefied fully developed flow of a gas through a duct of a triangular cross section is solved in the whole range of the Knudsen number. The flow is modelled by the BGK kinetic equation, subject to Maxwell diffuse ...
Kinetic modeling of a tapered Holweck pump
(2014)
The Holweck pump is a device widely used in many pumping systems. It can be a self-standing device or part of a multi-stage system, usually combined with a turbo-molecular pump (TMP). In the present work, an existing ...
Shear driven micro-flows of gaseous mixtures
(2006)
A mesoscale kinetic-type approach is proposed to solve shear driven micro flows of binary gas mixtures in MEMS. The coupled linear integro-differential equations, which formally describe the flow, are solved using the ...
WILLINGNESS TO PAY FOR RESIDENTIAL WATER USING STATED PREFERENCE ANALYSIS: THE CASE OF VOLOS, GREECE
(2014)
In the present research a questionnaire survey was performed with personal interviews in households in the city of Volos, Greece, in order to determine the willingness to pay for changes in the water service level using ...