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Hypertension in chronic kidney disease: Novel insights
(2020)
Management of arterial hypertension in patients with chronic kidney disease (CKD) remains a major challenge due to its high prevalence and associations with cardiovascular disease (CVD) and CKD progression. Several clinical ...
A comparative analysis between proteasome and immunoproteasome inhibition in cellular and humoral alloimmunity
(2017)
Triggered by the successful administration of the proteasome inhibitor bortezomib in kidney transplant recipients with acute or chronic antibody-mediated rejection, we evaluated the effect of the proteasome inhibitor ...
Upper extremity emergencies during SARS-COV-2 pandemic: Turnout trends
(2021)
Introduction: During the SARS-COV-2 pandemic and consequent government measures to prevent the overwhelming of public hospitals, emergency department (ED) orthopaedic turnout was significantly altered. This study compared ...
The outcome after surgical vs nonsurgical treatment of chronic subdural hematoma with dexamethasone
(2019)
Background: To determine the patient outcomes of retrospectively collected data between surgical versus nonsurgical treatment of chronic subdural hematoma (CSDH) with Dexamethasone (DX). Methods: This was a retrospective ...
Exercise training reduces alcohol consumption but does not affect HPA-axis activity in heavy drinkers
(2017)
Background It has been suggested that physical exercise could have potential beneficial effects in substance abusers, which are based on both physiological and psychological theories. Although a few studies have examined ...
Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017
(2018)
Background: Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 ...
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
(2016)
Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the elderly, with limited therapeutic options. Here we report on a study of >12 million variants, including 163,714 directly genotyped, ...
Could IGF-I levels play a neuroprotective role in patients with large vestibular schwannomas?
(2018)
Aim: To evaluate the possible superiority of outcome in patients with elevated IGF-I levels after vestibular schwannoma (VS) resection. Patients & methods: This retrospective study included 65 patients (34 male, 52.3%) ...
Magnetic resonance morphometry of the adult normal lumbar intervertebral space
(2018)
Purpose: This study aims to: (a) quantify and evaluate normal relationships between neighboring spinal units using MR imaging indices, (b) propose an easy-to-apply-and-reproduce method of estimating the correct amount of ...
Guidelines for the first-line treatment of restless legs syndrome/Willis-Ekbom disease, prevention and treatment of dopaminergic augmentation: A combined task force of the IRLSSG, EURLSSG, and the RLS-foundation
(2016)
A Task Force was established by the International Restless Legs Syndrome Study Group (IRLSSG) in conjunction with the European Restless Legs Syndrome Study Group (EURLSSG) and the RLS Foundation (RLS-F) to develop ...