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Multiple sclerosis: Shall we target cd33?
(2020)
Background: Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS). Myeloid lineage cells (microglia and macrophages) may participate in the pathogenic mechanisms leading to MS. CD33 is a transmembrane ...
Prevalence of C9orf72 hexanucleotide repeat expansion in Greek patients with sporadic ALS
(2020)
A total of 178 consecutive patients with definite sALS without frontotemporal dementia (FTD) were enrolled in this study, after complete clinical evaluation. A Repeat-Primed Polymerase Chain Reaction (RP-PCR) protocol was ...
Cost Effectiveness of Exenatide Once Weekly Versus Insulin Glargine and Liraglutide for the Treatment of Type 2 Diabetes Mellitus in Greece
(2018)
Objective: The objective of this study was to evaluate the long-term cost effectiveness of exenatide once weekly (ExQW) versus insulin glargine (IG) or liraglutide 1.2 mg (Lira1.2mg) for the treatment of adult patients ...
SLC2A1 Tag SNPs in Greek Patients with Diabetic Retinopathy and Nephropathy
(2019)
Backround: Genetic variants are implicated in the development of diabetic retinopathy (DR) and nephropathy (DN). The role of solute carrier family 2-facilitated glucose transporter member 1 (SLC2A1), also known as glucose ...
Missed diagnosis and overtreatment of COPD among smoking primary care population in central Greece: old problems persist
(2018)
Background: The diagnosis of COPD is not always consistent with the Global Initiative for Chronic Obstructive Lung Disease (GOLD) strategy in daily clinical practice, especially in primary care. This study aimed to estimate ...
Norovirus waterborne outbreak in Chalkidiki, Greece, 2015: Detection of GI.P2_GI.2 and GII.P16_GII.13 unusual strains
(2019)
Noroviruses, along with rotaviruses, are among the leading causes of gastroenteritis worldwide and novel strains are periodically emerging. In August 2015, an unusual increase of gastroenteritis cases occurred in a touristic ...
Cardiovascular risk factors in HIV infected individuals: Comparison with general adult control population in Greece
(2020)
Background Although combined antiretroviral therapy has substantially improved the prognosis of people living with HIV (PLHIV), mortality remains higher compared to the general population, mainly due to higher prevalence ...