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T-cells and B-cells in systemic sclerosis
(2010)
Systemic sclerosis (SSc) is characterized by activation of fibroblasts with extensive deposition of collagen, by small vessel vasculopathy with fibrointimal proliferation, and activation of the immune system, with hyper-γ- ...
Mycophenolate for the treatment of autoimmune hepatitis: Prospective assessment of its efficacy and safety for induction and maintenance of remission in a large cohort of treatment-naïve patients
(2011)
Background & Aims: Standard therapy for autoimmune hepatitis (AIH) is corticosteroids with or without azathioprine. However, 20% of patients do not respond or are intolerant to conventional treatment. Therefore, we evaluated ...
Unusual case of subarachnoid haemorrhage in patient with Fabry's disease: Case report and literature review
(2012)
Fabry's disease is a rare, X linked recessive disease affecting 1 in 40 000 persons. The symptoms result from a lack of or a non-functioning enzyme α galactosidase, which leads to globotriaosylceramide accumulation in the ...
External validation of the ASTRAL score to predict 3-and 12-month functional outcome in the china national stroke registry
(2013)
BACKGROUND AND PURPOSE-: The ASTRAL score was recently introduced as a prognostic tool for acute ischemic stroke. It predicts 3-month outcome reliably in both the derivation and the validation European cohorts. We aimed ...
Myocardial bridging evaluated with 128-multi detector computed tomography coronary angiography
(2010)
Purpose: The aim of the study was to evaluate the prevalence, length, depth, and location of myocardial bridging of the coronary arteries using 128-multi detector computed tomography coronary angiography. Methods: The study ...
Epidermal growth factor in the treatment of diabetic foot ulcers: An update
(2012)
Management of diabetic foot ulcers remains a rather challenging task. Epidermal growth factor (EGF) plays a central role in wound healing. It acts on epithelial cells and fibroblasts promoting restoration of damaged ...
Graphical and demographic synopsis of the captive cohort method for estimating population age structure in the wild
(2012)
The purpose of this paper is to complement the literature concerned with the captive cohort method for estimating age structure including (1) graphic techniques to visualize and thus better understand the underlying life ...
Pleural transport physiology: Insights from biological marker measurements in transudates
(2011)
Aims: The aim of this study was to evaluate the physicochemical properties of the pleural mesothelial barrier and of the biological markers that facilitate or eliminate the passage of molecules through the pleura. Methods ...
Cold shock Y-box protein-1 proteolysis autoregulates its transcriptional activities
(2013)
Background: The Y-box protein-1 (YB-1) fulfills pleiotropic functions relating to gene transcription, mRNA processing, and translation. It remains elusive how YB-1 shuttling into the nuclear and cytoplasmic compartments ...
Efficiency assessment across homogeneous specialty clinics in the region of thessaly, Greece
(2012)
Background: Hospital care expenditure is the most significant cost driver in the health care sector. Reductions in public hospitals' expenses are among the principal austerity measures included in the memorandum recommendations. ...