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Novel oligomeric proanthocyanidin derivatives interact with membrane androgen sites and induce regression of hormone-independent prostate cancer
(2011)
Prostate cancer is the most common malignancy among men in Western societies, and current therapeutic approaches are evolving to manage growth, recurrence, and mortality neoplasia. Membrane androgen receptors (mARs) have ...
Patient-Reported Selective Adherence to Heart Failure Self-Care Recommendations: A Prospective Cohort Study: The Atlanta Cardiomyopathy Consortium
(2013)
Simultaneous adherence with multiple self-care instructions among heart failure (HF) patients is not well described. Patient-reported adherence to 8 recommendations related to exercise, alcohol, medications, smoking, diet, ...
MEIS1 and BTBD9: Genetic association with restless leg syndrome in end stage renal disease
(2011)
Background: Restless legs syndrome (RLS) is a sleep related movement disorder that occurs both in an idiopathic form and in symptomatic varieties. RLS is a frequent and distressing comorbidity in end stage renal disease ...
Spontaneous traumatic macular hole closure in a 50-year-old woman: A case report
(2011)
Introduction. Traumatic macular holes (TMH) are well-known complications of ocular contusion injury. Spontaneous closure occurs in approximately 50% of cases, but rarely after the age of thirty. We report a case of spontaneous ...
Ticagrelor and prasugrel: Two novel, most-promising antiplatelet agents
(2010)
The need for safe and effective antiplatelet agents motivates scientists towards a non-ceasing research which has through the past few years provided patients suffering from coronary artery disease, submitted or not to ...
Verbal fluency in adults diagnosed with attention-deficit hyperactivity disorder (ADHD) in childhood
(2013)
It has been increasingly believed that attention-deficit hyperactivity disorder (ADHD) is a disorder with lifelong course associated with cognitive difficulties including among others, language production, verbal learning, ...
Radiological and radiotherapeutic approaching of pediatric tumors in head and neck area
(2013)
The most common pediatric malignancies in head and neck area consisted of lymphoma, leukemia, brain tumors, neuroblastoma, Wilms' tumor, sarcomas and primarily rhabdomyosarcoma. This review reports in brief radiological ...
Hereditary hyperferritinemia cataract syndrome as a cause of childhood hyperferritinemia
(2014)
A 2-year-old female was presented with high levels of serum ferritin (890 ng/mL) in a routine blood test. Clinical and laboratory investigations excluded the presence of iron overload and secondary causes of hyperferritinemia. ...
Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: A systems biology based approach
(2010)
To identify novel genes and pathways associated with AMD, we performed microarray gene expression and linkage analysis which implicated the candidate gene, retinoic acid receptor-related orphan receptor alpha (RORA, 15q). ...
Systemic sclerosis: From pathogenesis towards targeted immunotherapies
(2012)
Systemic sclerosis (SSc), a chronic disease with widespread collagen deposition, has three pathogenetic facets: immune activation, microvasculopathy and fibroblast activation. Immune activation and microvasculopathy occur ...