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Late HDV RNA relapse after peginterferon alpha-based therapy of chronic hepatitis delta
(2014)
Interferon alpha is the only treatment option for hepatitis delta virus (HDV). Trials investigating the efficacy of pegylated interferon alpha (PEG-IFNa) showed HDV RNA negativity rates of 25-30% 24 weeks after therapy. ...
High-dose pantoprazole continuous infusion is superior to somatostatin after endoscopic hemostasis in patients with peptic ulcer bleeding
(2007)
BACKGROUND: The best antisecretory treatment after endoscopic hemostasis in patients with ulcer bleeding is still in quest. OBJECTIVES: To compare pantoprazole and somatostatin continuous infusion after endoscopic hemostasis ...
Vascularized compared with nonvascularized fibular grafting for the treatment of osteonecrosis of the femoral head
(2003)
Background: We are not aware of any clinical studies in the literature comparing the results of vascularized and non- vascularized fibular grafting for the treatment of osteonecrosis of the femoral head. The purpose of ...
Validation of the Augmentation Severity Rating Scale (ASRS): A multicentric, prospective study with levodopa on restless legs syndrome
(2007)
Background: Augmentation is the main complication during long-term dopaminergic treatment of restless legs syndrome (RLS) and reflects an overall increase in RLS severity. Its severity varies considerably from a minor ...
Treatment of high risk myelodysplastic syndromes with idarubicin and cytosine arabinoside supported by granulocyte-macrophage colony-stimulating factor (GM-CSF)
(1996)
In this prospective study, patients with 'high risk' primary MDS, namely RAEB or RAEBt, were treated with combination chemotherapy (CT) supported by GM-CSF. The induction CT consisted of idarubicin 6 mg/m2 days 1-3 and ...
Laparoscopic cholecystectomy under spinal anesthesia: A pilot study
(2006)
Background: Regional anesthesia has not been used as the sole anesthetic procedure other than in the scenario of a patient at high risk to undergo laparoscopic cholecystectomy with CO2 pneumoperitoneum under general ...
Effect of mifepristone on folliculogenesis in women treated with recombinant FSH
(1997)
Objective: To study the mechanism through which mifepristone interrupts folliculogenesis. Design: Normally ovulating women undergoing donor intrauterine insemination (IUI) treatment were investigated during two menstrual ...
Lamivudine plus interleukin-12 combination therapy in chronic hepatitis B: Antiviral and immunological activity
(2005)
Interleukin-12 (IL-12) is an immunomodulatory cytokine that promotes cellular immunity. Pre-clinical data suggest that IL-12 inhibits hepatitis B virus (HBV) replication by stimulating interferon-gamma (IFN-γ) production. ...
Uncommon leg ulcers in the lower extremity
(2007)
Objective: To determine the prevalence of uncommon ulcers, unrelated to venous or arterial etiology, in patients presenting to vascular clinics. Methods: This was a multicenter prospective study of consecutive patients ...
Early gastrostomy reduces the rate of ventilator-associated pneumonia in stroke or head injury patients
(2005)
Presence of a nasogastric tube is a risk factor for the development of ventilator-associated pneumonia (VAP). Alternatively, gastrostomy can be used for administration of enteral feedings. To determine whether early ...