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Lessons from pathophysiology: Use of individualized combination treatments with immune interventional agents to tackle severe respiratory failure in patients with COVID-19
(2021)
Aims Infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) may lead to the development of severe respiratory failure. In hospitalized-patients, prompt interruption of the virus-driven inflammatory process ...
Relationship between nitrate headache and outcome in patients with acute stroke: Results from the efficacy of nitric oxide in stroke (ENOS) trial
(2021)
Introduction Nitrate-induced headache is common and may signify responsive cerebral vasculature. We assessed the relationship between nitrate headache and outcome in patients with acute stroke. Materials and methods Patients ...
Appetite control across the lifecourse: The acute impact of breakfast drink quantity and protein content. the full4health project
(2020)
Understanding the mechanisms of hunger, satiety and how nutrients affect appetite control is important for successful weight management across the lifecourse. The primary aim of this study was to describe acute appetite ...
Low-Grade Systemic Inflammation Interferes with Anabolic and Catabolic Characteristics of the Aged Human Skeletal Muscle
(2021)
Aging is associated with the development of chronic low-grade systemic inflammation (LGSI) characterized by increased circulating levels of proinflammatory cytokines and acute phase proteins such as C-reactive protein ...
Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology
(2022)
Back pain is a common and debilitating disorder with largely unknown underlying biology. Here we report a genome-wide association study of back pain using diagnoses assigned in clinical practice; dorsalgia (119,100 cases, ...
Obesity and long-term outcomes after incident stroke: a prospective population-based cohort study
(2021)
Background: The association between obesity, major adverse cardiovascular events (MACE), and mortality in patients with incident stroke is not well established. We assessed the relationship between body mass index (BMI) ...
Prevalence of uncoupling protein one genetic polymorphisms and their relationship with cardiovascular and metabolic health
(2022)
Contribution of UCP1 single nucleotide polymorphisms (SNPs) to susceptibility for cardiometabolic pathologies (CMP) and their involvement in specific risk factors for these conditions varies across populations. We tested ...
Late results of a randomized trial on the role of mild hypofractionated radiotherapy for the treatment of localized prostate cancer
(2020)
Background: Prostate cancer is considered to be highly sensitive to changes in radiation therapy dose per fraction, specifically to hypofractionation. An increase in the fractionation dose could cause a higher increase to ...
Cross-cultural validation of the start back screening tool in a Greek low back pain sample
(2021)
Background: Keele STarT Back Screening Tool (SBST) is a popular 9-item prognostic recovery questionnaire for low back pain (LBP) with validation studies in several cultural settings, but not Greek. Objectives: The ...
Organochlorine pesticide levels in Greek patients with Parkinson's disease
(2020)
Background: Parkinson's disease (PD) is a neurodegenerative disease, mostly presenting with characteristic motor symptoms. Organochlorines (OC) are a class of widely-used pesticides that have been included among the list ...