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Lipopolysaccharide and hypoxia significantly alters interleukin-8 and macrophage chemoattractant protein-1 production by human fibroblasts but not fibrosis related factors
(2011)
Besides extracellular matrix production, fibroblasts are able to produce various cytokines. Their ubiquitous position makes fibroblasts appropriate cells for sensing various noxious stimuli and for attracting immune cells ...
Differential diagnosis of hyperkalemia: an update to a complex problem
(2012)
Hyperkalemia is a relative common and sometimes life threatening electorlyte disorder. Although its symptomatic treatment is relatively easy, since precise therapeutic algorithms are available, its differential diagnosis ...
Infections in hemodialysis: a concise review. Part II: blood transmitted viral infections
(2011)
Hemodialysis (HD) patients are particularly predisposed to infections. It seems that the HD procedure per se as well as disturbances in both innate and adaptive immunity significantly contribute to this susceptibility. ...
Infections in hemodialysis: a concise review - Part 1: bacteremia and respiratory infections
(2011)
Hemodialysis (HD) patients are particularly predisposed to infections. It seems that the HD procedure per se as well as disturbances in both innate and adaptive immunity significantly contribute to this susceptibility. ...
Uric acid induces caspase-1 activation, IL-1 beta secretion and P2X7 receptor dependent proliferation in primary human lymphocytes
(2013)
Background: Urate through Nacht Domain, Leucine-Rich Repeat, and pyrin domain-containing protein 3 (NALP3) dependent caspase-1 activation stimulates macrophages to secrete inteleukin-1 beta (IL-1 beta). Purinergic receptor ...
Urate crystals induce NLRP3 inflammasome-dependent IL-1 beta secretion and proliferation in isolated primary human T-cells
(2015)
Background: Urate through NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome-dependent caspase-1 activation stimulates macrophages to secrete inteleukin-1 beta (IL-1 beta). Urate also enhances adaptive ...