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Albumin possesses intrinsic enolase activity towards dihydrotestosterone which can differentiate benign from malignant breast tumors
(1999)
Serum albumin was found to possess enolase activity towards the dihydrotestesterone (DHT) molecule, converting it from its 3-keto to 3-enol form. This activity was accompanied by albumin during all stages of purification, ...
Chemopreventive activity of very low dose dietary tannic acid administration in hepatoma bearing C3H male mice
(1999)
Tannins are plant polyphenols comprising a heterogeneous group of compounds. Tannic acid is a common tannin found in tea, coffee, immature fruits, etc. and it has also been used as a food additive. An increasing body of ...
Enzymatic conversion of dihydrotestosterone from 3-keto to 3-enol form in the rat prostate
(1996)
Dihydrotestosterone (DHT) is the active androgen, as well as a strong tumor promoter in the prostate, where several enzymes are essential for the regulation of its activity. We localized four enzymes promoting the enolization ...
CDK-inhibitor olomoucine inhibits cell death after exposure of cell lines to cytosine-arabinoside
(1999)
Signal transduction for apoptosis or programmed cell death, after DNA damage in mammalian cells, is believed to involve activation of cyclin-dependent kinases (CDKs), especially CDK-1 (cdc2) and CDK-2. We used CDK-inhibitor ...
Can traditional epidemiology detect cancer risks caused by occupational exposure to pesticides?
(1999)
In order to investigate the possible relationship between cancer and occupational exposure to pesticides, we reviewed the latest literature of the epidemiological studies in this area coming to the conclusion that, while ...
CHARACTERIZATION OF THE PROTEIN PROTECTING RNA FROM ACID PRECIPITATION AND ITS EVALUATION AS TUMOR-MARKER IN GASTROINTESTINAL AND GYNECOLOGICAL CANCER
(1995)
In a previous study, we observed increased protective activity against acid precipitation of poly (U) in the serum of tumor bearing mice and hepatoma patients. In the present study we purified and partially characterized ...