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Gossypol-induced inhibition of plasminogen activator activity in human and ovine acrosomal extract
(1999)
The effect of gossypol-a polycyclic compound isolated from cotton seeds-on the plasminogen activator activity of man and ram acrosomal extracts was explored in vitro. The action of gossypol on the plasminogen activator ...
Albumin possesses intrinsic enolase activity towards dihydrotestosterone which can differentiate benign from malignant breast tumors
(1999)
Serum albumin was found to possess enolase activity towards the dihydrotestesterone (DHT) molecule, converting it from its 3-keto to 3-enol form. This activity was accompanied by albumin during all stages of purification, ...
Chemopreventive activity of very low dose dietary tannic acid administration in hepatoma bearing C3H male mice
(1999)
Tannins are plant polyphenols comprising a heterogeneous group of compounds. Tannic acid is a common tannin found in tea, coffee, immature fruits, etc. and it has also been used as a food additive. An increasing body of ...
Tannins, xenobiotic metabolism and cancer chemoprevention in experimental animals
(1999)
Tannins are plant polyphenolic compounds that are contained in large quantities in food and beverages (tea, red wine, nuts, etc.) consumed by humans daily. It has been shown that various tannins exert broad cancer ...
Lipid peroxidation and tissue damage
(1999)
In recent years it has become apparent that the oxidation of lipids, or lipid peroxidation, is a crucial step in the pathogenesis of several disease states in adult and infant patients. Lipid peroxidation is a process ...
Sex hormone binding globulin of the plasma: Towards understanding of a new regulatory system in steroid hormone action
(1999)
Sex hormone binding globulin (SHBG) is a protein that circulates in the plasma of many species and binds with high affinity to sex steroids in the human and primates, while it is androgen-binding protein in many animals ...
Dexamethasone has a biphasic effect on the c-Jun mRNA expression in the fetal and adult rat lung, in vivo
(1999)
Glucocorticoids are a very potent therapy for the treatment of asthma as well for lung maturation in the prematurely newborn animals and human. It has been demonstrated that glucocorticoid receptors antagonize the actions ...
Dexamethasone has a biphasic effect on the c-Jun m-RNA expression in the fetal and adult rat lung, in vivo
(1999)
Glucocorticoids are a very potent therapy for the treatment of asthma as well for lung maturation in the prematurely newborn animals and human. It has been demonstrated that glucocorticoid receptors antagonize the actions ...
CDK-inhibitor olomoucine inhibits cell death after exposure of cell lines to cytosine-arabinoside
(1999)
Signal transduction for apoptosis or programmed cell death, after DNA damage in mammalian cells, is believed to involve activation of cyclin-dependent kinases (CDKs), especially CDK-1 (cdc2) and CDK-2. We used CDK-inhibitor ...
Can traditional epidemiology detect cancer risks caused by occupational exposure to pesticides?
(1999)
In order to investigate the possible relationship between cancer and occupational exposure to pesticides, we reviewed the latest literature of the epidemiological studies in this area coming to the conclusion that, while ...