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Crohn's disease-specific anti-CUZD1 pancreatic antibodies are absent in ruminants with paratuberculosis

Liaskos, C.; Spyrou, V.; Athanasiou, L. V.; Orfanidou, T.; Mavropoulos, A.; Rigopoulou, E. I.; Amiridis, G. S.; Shoenfeld, Y.; Billinis, C.; Bogdanos, D. P. (2015)

Background: Pancreatic autoantibodies (PABs) specifically recognizing GP2 and/or CUZD1 are present in more than 35% of patients with Crohn's disease (CrD). We have recently provided evidence of the presence of GP2-specific ...

Antimitochondrial antibodies of immunoglobulin G3 subclass are associated with a more severe disease course in primary biliary cirrhosis

Rigopoulou, E. I.; Davies, E. T.; Bogdanos, D. P.; Liaskos, C.; Mytilinaiou, M.; Koukoulis, G. K.; Dalekos, G. N.; Vergani, D. (2007)

Background/Aims: Primary biliary cirrhosis (PBC) is characterised by the presence of immunoglobulin (Ig) G antimitochondrial antibodies (AMA), which are routinely detected by indirect immunofluorescence (IFL) using composite ...

Bone marrow findings in patients with autoimmune liver diseases

Tsikrikoni, A.; Rigopoulou, E. I.; Zachou, K.; Liaskos, C.; Kyriakou, D.; Dalekos, G. N. (2008)

Background and Aims: We have recently reported quantitative and qualitative differences of the bone marrow (BM) hematopoietic progenitor cells in autoimmune hepatitis type-1 (AIH-1) and primary biliary cirrhosis (PBC). In ...

Infectome: A platform to trace infectious triggers of autoimmunity

Bogdanos, D. P.; Smyk, D. S.; Invernizzi, P.; Rigopoulou, E. I.; Blank, M.; Pouria, S.; Shoenfeld, Y. (2013)

The "exposome" is a term recently used to describe all environmental factors, both exogenous and endogenous, which we are exposed to in a lifetime. It represents an important tool in the study of autoimmunity, complementing ...

Association between the primary biliary cirrhosis specific anti-sp100 antibodies and recurrent urinary tract infection

Bogdanos, D. P.; Baum, H.; Butler, P.; Rigopoulou, E. I.; Davies, E. T.; Ma, Y.; Burroughs, A. K.; Vergani, D. (2003)

Background and aims. Recurrent urinary tract infections (rUTI) have been suggested to be involved in the induction of anti-mitochondrial antibodies (AMA), the serological hallmark of primary biliary cirrhosis (PBC), in ...

Anti-sp100 antibodies in primary biliary cirrhosis

Rigopoulou, E. I.; Dalekos, G. N. (2004)

Diagnostic relevance and clinical significance of the new enhanced performance M2 (MIT3) ELISA for the detection of IgA and IgG antimitochondrial antibodies in primary biliary cirrhosis

Gabeta, S.; Norman, G. L.; Liaskos, C.; Papamichalis, P. A.; Zografos, T.; Garagounis, A.; Rigopoulou, E. I.; Dalekos, G. N. (2007)

Background/aims: Antimitochondrial antibodies (AMAs) are the serological hallmark of primary biliary cirrhosis (PBC). We evaluated the sensitivity and specificity of a new M2 enhanced performance enzyme-linked immunosorbent ...

Prevalence of gastric parietal cell antibodies and intrinsic factor antibodies in primary biliary cirrhosis

Liaskos, C.; Norman, G. L.; Moulas, A.; Garagounis, A.; Goulis, I.; Rigopoulou, E. I.; Dalekos, G. N. (2010)

Background: We investigated the prevalence of antibodies against gastric parietal cells (GPA), intrinsic factor antibodies (IFA) and the presence of pernicious anemia in a large cohort of primary biliary cirrhosis (PBC) ...

IgA anti-b2GPI antibodies in patients with autoimmune liver diseases

Gabeta, S.; Norman, G. L.; Gatselis, N.; Liaskos, C.; Papamichalis, P. A.; Garagounis, A.; Zachou, K.; Rigopoulou, E. I.; Dalekos, G. N. (2008)

Introduction Recently, we reported a high prevalence of immunoglobulin G and/or immunoglobulin M anticardiolipin antibodies (aCL) in patients with autoimmune liver diseases, namely, autoimmune hepatitis (AIH), primary ...

Diagnostic and clinical utility of antibodies against the nuclear body promyelocytic leukaemia and Sp100 antigens in patients with primary biliary cirrhosis

Mytilinaiou, M. G.; Meyer, W.; Scheper, T.; Rigopoulou, E. I.; Probst, C.; Koutsoumpas, A. L.; Abeles, D.; Burroughs, A. K.; Komorowski, L.; Vergani, D.; Bogdanos, D. P. (2012)

Background: The lack of an immunoassay that detects antibodies to promyelocytic leukaemia (PML) protein, the primary biliary cirrhosis (PBC)-specific multiple nuclear dot (MND) antigen, has prompted us to develop a line ...