Search

Now showing items 1-10 of 32

Crohn's disease-specific anti-CUZD1 pancreatic antibodies are absent in ruminants with paratuberculosis

Liaskos, C.; Spyrou, V.; Athanasiou, L. V.; Orfanidou, T.; Mavropoulos, A.; Rigopoulou, E. I.; Amiridis, G. S.; Shoenfeld, Y.; Billinis, C.; Bogdanos, D. P. (2015)

Background: Pancreatic autoantibodies (PABs) specifically recognizing GP2 and/or CUZD1 are present in more than 35% of patients with Crohn's disease (CrD). We have recently provided evidence of the presence of GP2-specific ...

P38 MAPK signaling in pemphigus: Implications for skin autoimmunity

Mavropoulos, A.; Orfanidou, T.; Liaskos, C.; Smyk, D. S.; Spyrou, V.; Sakkas, L. I.; Rigopoulou, E. I.; Bogdanos, D. P. (2013)

p38 mitogen activated protein kinase (p38 MAPK) signaling plays a major role in the modulation of immune-mediated inflammatory responses and therefore has been linked with several autoimmune diseases. The extent of the ...

The Role of p38 MAPK in the Aetiopathogenesis of Psoriasis and Psoriatic Arthritis

Mavropoulos, A.; Rigopoulou, E. I.; Liaskos, C.; Bogdanos, D. P.; Sakkas, L. I. (2013)

The pathogenetic mechanisms responsible for the induction of immune-mediated disorders, such as psoriasis, remain not well characterized. Molecular signaling pathways are not well described in psoriasis, as well as psoriatic ...

HELICOBACTER PYLORI AS A TRIGGER OF SYSTEMIC SCLEROSIS: IMMUNOLOGICAL ASPECTS

Liaskos, C.; Varna, A.; Simopoulou, T.; Mavropoulos, A.; Mytilinaiou, M.; Rigopoulou, E. I.; Bogdanos, D. P.; Sakkas, L. I. (2014)

CUZD1 and Anti-CUZD1 Antibodies as Markers of Cancer and Inflammatory Bowel Diseases

Liaskos, C.; Rigopoulou, E. I.; Orfanidou, T.; Bogdanos, D. P.; Papandreou, C. N. (2013)

CUZD1, the CUB, and zona pellucida-like domains-containing protein 1, is a newly identified antigen of pancreatic autoantibodies (PAB) giving a reticulogranular pattern in patients with inflammatory bowel diseases, and in ...

Autoimmune hepatitis-specific antibodies against soluble liver antigen and liver cytosol type 1 in patients with chronic viral hepatitis

Rigopoulou, E. I.; Mytilinaiou, M.; Romanidou, O.; Liaskos, C.; Dalekos, G. N. (2007)

Background. Non-organ specific autoantibodies are highly prevalent in patients with chronic hepatitis C (HCV). Among them, anti-liver kidney microsomal type 1 (LKM1) antibody - the serological marker of type 2 autoimmune ...

Ileal InflammationMay Trigger the Development of GP2-Specific Pancreatic Autoantibodies in Patients with Crohn's Disease

Pavlidis, P.; Romanidou, O.; Roggenbuck, D.; Mytilinaiou, M. G.; Al-Sulttan, F.; Liaskos, C.; Smyk, D. S.; Koutsoumpas, A. L.; Rigopoulou, E. I.; Conrad, K.; Forbes, A.; Bogdanos, D. P. (2012)

Why zymogen glycoprotein 2 (GP2), the Crohn's disease (CD)-specific pancreatic autoantigen, is the major target of humoral autoimmunity in inflammatory bowel diseases (IBD) is uknown. Recent evidence demonstrates that GP2 ...

Anti-mitochondrial antibody immunofluorescent titres correlate with the number and intensity of immunoblot-detected mitochondrial bands in patients with primary biliary cirrhosis

Rigopoulou, E. I.; Bogdanos, D. P.; Liaskos, C.; Koutsoumpas, A.; Baum, H.; Vergani, D.; Dalekos, G. N. (2007)

Background: Primary biliary cirrhosis (PBC)-specific anti-mitochondrial antibodies (AMA), routinely detected by indirect immunofluoresnce, immunofix various mitochondrial antigens by immunoblot (IB). We have investigated ...

Occult hepatitis B virus infection in patients with autoimmune liver diseases

Georgiadou, S. P.; Zachou, K.; Liaskos, C.; Gabeta, S.; Rigopoulou, E. I.; Dalekos, G. N. (2009)

Occult hepatitis B virus (HBV) infection is characterized by undetectable serum HBV surface antigen (HBsAg) but detectable HBV-DNA in serum or liver. To determine the prevalence and clinical impact of occult HBV in autoimmune ...

Crohn's disease-specific pancreatic autoantibodies are specifically present in ruminants with paratuberculosis: Implications for the pathogenesis of the human disease

Liaskos, C.; Spyrou, V.; Roggenbuck, D.; Athanasiou, L. V.; Orfanidou, T.; Mavropoulos, A.; Reinhold, D.; Rigopoulou, E. I.; Amiridis, G. S.; Billinis, C.; Bogdanos, D. P. (2013)

Mycobacterium avium subspecies paratuberculosis (MAP) induces paratuberculosis (ptb) in ruminants and has clinical and histological features resebling Crohn's disease (CD). Pancreatic autoantibodies (PAB) targeting ...