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Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration
(2011)
Vitamin D has been shown to have anti-angiogenic properties and to play a protective role in several types of cancer, including breast, prostate and cutaneous melanoma. Similarly, vitamin D levels have been shown to be ...
Daptomycin use in patients with osteomyelitis: A preliminary report from the EU-CORESM database
(2013)
Background: Osteomyelitis is a complex and heterogeneous group of infections that require surgical and antimicrobial interventions. Because treatment failure or intolerance is common, new treatment options are needed. ...
Verbal fluency in adults diagnosed with attention-deficit hyperactivity disorder (ADHD) in childhood
(2013)
It has been increasingly believed that attention-deficit hyperactivity disorder (ADHD) is a disorder with lifelong course associated with cognitive difficulties including among others, language production, verbal learning, ...
Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: A systems biology based approach
(2010)
To identify novel genes and pathways associated with AMD, we performed microarray gene expression and linkage analysis which implicated the candidate gene, retinoic acid receptor-related orphan receptor alpha (RORA, 15q). ...
Immunoglobulin D myeloma: Clinical features and outcome in the era of novel agents
(2014)
Objectives: Immunoglobulin D (IgD) multiple myeloma is an uncommon variant of the disease probably associated with poorer prognosis. However, data on IgD myeloma patients treated in the novel agent era are lacking. Methods: ...
Ocular disease awareness and pattern of ocular manifestation in patients with biopsy-proven lung sarcoidosis
(2011)
Purpose: The aim of this research is to study the patterns of ocular involvement in patients with biopsy-proven lung sarcoidosis and estimate the level of patients' awareness of possible ocular complications of sarcoidosis. ...
The role of learning and customer orientation for delivering service quality to patients
(2010)
Purpose: This study seeks to investigate the impact that learning orientation, internal and external customer orientation have on quality of care delivered to patients. Additionally, given the differences between managerial ...
Erosive hand osteoarthritis is associated with subclinical atherosclerosis and endothelial dysfunction
(2013)
Chronic inflammatory disorders have been associated with accelerated atherosclerosis and increased cardiovascular (CV) risk. Recent evidence suggests that erosive hand osteoarthritis (EOA) has considerable inflammation; ...
Smoking habits, attitudes and training among medical students of the Democritus University of Thrace
(2012)
Introduction Tobacco use continues to be the leading global cause of preventable death, contributing to the death of nearly 6 million people each year. Medical students, who are future doctors, have an important role to ...
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22
(2011)
Objectives: Osteoarthritis (OA) is the most prevalent form of arthritis and accounts for substantial morbidity and disability, particularly in older people. It is characterised by changes in joint structure, including ...