Browsing by Subject "protein MutL"

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Embryological results of couples undergoing ICSI-ET treatments with males carrying the single nucleotide polymorphism rs175080 of the MLH3 gene

Anifandis G., Markandona O., Dafopoulos K., Messini C., Tsezou A., Dimitraki M., Georgoulias P., Daponte A., Messinis I. (2017)

Human MLH3 (hMLH3) gene has been suggested to play a role in the DNA mismatch repair mechanism, while it may also be associated with abnormal spermatogenesis and subsequently male infertility. The aim of the present study ...
Single-nucleotide polymorphism rs 175080 in the MLH3 gene and its relation to male infertility

Markandona O., Dafopoulos K., Anifandis G., Messini C.I., Dimitraki M., Tsezou A., Georgoulias P., Messinis I.E. (2015)

Purpose: MLH3, a MutL homolog protein in mammals playing a role in DNA mismatch repair, is associated with spermatogenesis and male infertility. The purpose of the present study was to investigate the association of the ...