Now showing items 1-3 of 3

    • Bortezomib reverses the proliferative and antiapoptotic effect of neuropeptides on prostate cancer cells 

      Tsapakidis, K.; Vlachostergios, P. J.; Voutsadakis, I. A.; Befani, C. D.; Patrikidou, A.; Hatzidaki, E.; Daliani, D. D.; Moutzouris, G.; Liakos, P.; Papandreou, C. N. (2012)
      Objectives: Neuropeptides are important signal initiators in advanced prostate cancer, partially acting through activation of nuclear factor kappa B. Central to nuclear factor kappa B regulation is the ubiquitin-proteasome ...
    • Cold shock Y-box protein-1 proteolysis autoregulates its transcriptional activities 

      Van Roeyen, C. R. C.; Scurt, F. G.; Brandt, S.; Kuhl, V. A.; Martinkus, S.; Djudjaj, S.; Raffetseder, U.; Royer, H. D.; Stefanidis, I.; Dunn, S. E.; Dooley, S.; Weng, H.; Fischer, T.; Lindquist, J. A.; Mertens, P. R. (2013)
      Background: The Y-box protein-1 (YB-1) fulfills pleiotropic functions relating to gene transcription, mRNA processing, and translation. It remains elusive how YB-1 shuttling into the nuclear and cytoplasmic compartments ...
    • Protein misfolding in neurodegenerative diseases 

      Agorogiannis, E. I.; Agorogiannis, G. I.; Papadimitriou, A.; Hadjigeorgiou, G. M. (2004)
      A common pathogenic mechanism shared by diverse neurodegenerative disorders, like Alzheimer's disease, Parkinson's disease, Huntington's disease and transmissible spongiform encephalopathies, may be altered protein homeostasis ...