Browsing by Subject "lactate dehydrogenase"
Now showing items 1-13 of 13
-
99mTc sestamibi as a prognostic factor of response to first-line therapy and outcome in patients with malignant lymphoma
(2013)INTRODUCTION: Resistance to chemotherapy poses a major problem in cancer patients. Although of multifactorial origin, some of the implicated mechanisms also interfere with Tc-MIBI uptake and retention in cancer cells. The ... -
Clinical immunology quiz - Case 1
(2007) -
Comparison between leg and arm eccentric exercises of the same relative intensity on indices of muscle damage
(2005)Many exercise models have demonstrated associations between eccentric muscle actions and muscle damage. However, the magnitude of muscle damage varies among the models. It appears that responses to eccentric exercise are ... -
Could IFN-γ predict the development of residual pleural thickening in tuberculous pleurisy?
(2008)Could IFN-γ predict the development of residual pleural thickening tuberculous pleurisy? I. Gerogianni, M. Papala, P. Tsopa, P. Zigoulis, A. Dimoulis, K. Kostikas, T. Kiropoulos, KI Gourgoulianis. Background. The aim of ... -
Dichloroacetate at therapeutic concentration alters glucose metabolism and induces regulatory t-cell differentiation in alloreactive human lymphocytes
(2013)Background: Most cancer cells rely on aerobic glycolysis. Dichloroacetate (DCA) inhibits aerobic glycolysis and is a promising relatively nontoxic anticancer compound. However, rapidly proliferating effector T-cells also ... -
Immunoglobulin D myeloma: Clinical features and outcome in the era of novel agents
(2014)Objectives: Immunoglobulin D (IgD) multiple myeloma is an uncommon variant of the disease probably associated with poorer prognosis. However, data on IgD myeloma patients treated in the novel agent era are lacking. Methods: ... -
Indoleamine 2,3-dioxygenase depletes tryptophan, activates general control non-derepressible 2 kinase and down-regulates key enzymes involved in fatty acid synthesis in primary human CD4+ T cells
(2015)Indoleamine 2,3-dioxygenase (IDO) is expressed in antigen-presenting cells and exerts immunosuppressive effects on CD4+ T cells. One mechanism is through the inhibition of aerobic glycolysis. Another prerequisite for T-cell ... -
Intense basketball-simulated exercise induces muscle damage in men with elevated anterior compartment pressure
(2004)The purpose of the present investigation was to examine the levels of muscle soreness, muscle damage, and performance output in men with (S, n = 24) or without (A, n = 24) chronic compartment syndrome (CACS)-related symptoms ... -
Malate dehydrogenase-2 inhibitor LW6 promotes metabolic adaptations and reduces proliferation and apoptosis in activated human T-cells
(2015)Activated T cells rely on aerobic glycolysis and glutaminolysis in order to proliferate and differentiate into effector cells. Therefore, intervention in these metabolic pathways inhibits proliferation. The aim of the ... -
Minimal invasive technique for gene delivery in porcine liver lobe segment
(2011)Introduction: The feasibility and outcome of large volume injection of gene solution in a segment of a liver lobe, without backflow, were studied in a porcine model, using a custom-designed balloon catheter. Method: Eight ... -
Salmonella enteritidis infection complicated by acute myocarditis: A case report and review of the literature
(2011)Salmonella spp. is the cause of commonly encountered infections, with seasonal pattern of occurrence and worldwide distribution. Some of the clinical manifestations such as gastroenteritis and bacteremia are common, whereas ... -
Targeting neuroendocrine prostate cancer: Molecular and clinical perspectives
(2015)Neuroendocrine prostate carcinoma, either co-present with the local adenocarcinoma disease or as a result of transdifferentiation later in time, was described as one major process of emerging resistance to androgen deprivation ... -
Unnecessary diagnostic investigations in benign acute childhood myositis: A case series report
(2012)Benign acute childhood myositis (BACM) is a rare, acute, self-limiting muscle disorder, mainly affecting school-aged boys, with an excellent prognosis, requiring no therapeutic intervention. We report a series of seven ...