Πλοήγηση ανά Θέμα "interleukin 2"

Anti-cd20 agents for multiple sclerosis: Spotlight on ocrelizumab and ofatumumab

Florou D., Katsara M., Feehan J., Dardiotis E., Apostolopoulos V. (2020)

Until recently, in the pathogenesis of Multiple Sclerosis (MS), the contribution of B cells has been largely underestimated, and the disease was considered a T-cell-mediated disorder. However, newer evidence shows that B ...

COVID-19 pandemic and cardiovascular disease: where do we stand?

Chatzis D.G., Magounaki K.T., Pantazopoulos I.N., Johnson E.O., Tsioufis K.P. (2020)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19) which recently has been characterized as a pandemic by the World Health Organization (WHO) having killed ...

Cytokines and pathological sleep

Kapsimalis, F.; Basta, M.; Varouchakis, G.; Gourgoulianis, K.; Vgontzas, A.; Kryger, M. (2008)

Cytokines are proteins produced by leukocytes and other cells that function as intercellular mediators acting on several target tissues, resulting in multiple biologic actions. Over the last decade, medical research has ...

Hepatitis D virus-specific cytokine responses in patients with chronic hepatitis delta before and during interferon alfa-treatment

Grabowski, J.; Yurdaydìn, C.; Zachou, K.; Buggisch, P.; Hofmann, W. P.; Jaroszewicz, J.; Schlaphoff, V.; Manns, M. P.; Cornberg, M.; Wedemeyer, H. (2011)

Background: Hepatitis delta is caused by infection with the hepatitis D virus (HDV) and is considered the most severe form of viral hepatitis. Treatment options for hepatitis delta are limited, with only 25% of patients ...

Mammary defences and immunity against mastitis in sheep

Katsafadou A.I., Politis A.P., Mavrogianni V.S., Barbagianni M.S., Vasileiou N.G.C., Fthenakis G.C., Fragkou I.A. (2019)

The objectives of this review paper are to present udder defences, including teat of the udder, mammary epithelial cells, leucocytes, immunoglobulins, complement systemand chemical antibacterial agents, to describe cooperation ...

Mapping interleukin enhancer binding factor 2 gene (ILF2) to human chromosome 1 (1q11-qter and 1p11-p12) by polymerase chain reaction amplification of human-rodent somatic cell hybrid DNA templates

Marcoulatos, P.; Koussidis, G.; Mamuris, Z.; Velissariou, V.; Vamvakopoulos, N. C. (1996)

Interleukin-2 (IL-2) is the first lymphokine secreted following T cell activation. Several transcription factors regulate IL-2 gene expression, including the nuclear factor of activated T cells (NFAT). NFAT acts at the ...

Melanoma: The Radiotherapeutic point of view; review of the current literature

Zygogianni, A.; Kyrgias, G.; Kouvaris, J.; Mystakidou, K.; Gogas, H.; Kouloulias, V. (2011)

Surgery remains the mainstay of melanoma therapy at all sites. Melanoma is widely believed to be a radioresistant tumor, a misconception that has historically led to the limited use of RT for its treatment. We searched ...

Microbiome in multiple sclerosis; where are we, what we know and do not know

Boziki M.K., Kesidou E., Theotokis P., Mentis A.-F.A., Karafoulidou E., Melnikov M., Sviridova A., Rogovski V., Boyko A., Grigoriadis N. (2020)

An increase of multiple sclerosis (MS) incidence has been reported during the last decade, and this may be connected to environmental factors. This review article aims to encapsulate the current advances targeting the study ...

p38 mitogen-activated protein kinase impairment of innate immune cells is a characteristic feature of HBeAg-negative chronic hepatitis B

Bakarozi M., Mavropoulos A., Bogdanos D.P., Dalekos G.N., Rigopoulou E.I. (2020)

The mitogen-activated protein kinase p38 (MAPK) is implicated in the induction of immune responses by regulating the differentiation of T lymphocytes and production of cytokines. Our aim was to investigate p38MAPK ...