Πλοήγηση ανά Συγγραφέα "Tsitsanou, K. E."

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Anopheles gambiae odorant binding protein crystal complex with the synthetic repellent DEET: implications for structure-based design of novel mosquito repellents

Tsitsanou, K. E.; Thireou, T.; Drakou, C. E.; Koussis, K.; Keramioti, M. V.; Leonidas, D. D.; Eliopoulos, E.; Iatrou, K.; Zographos, S. E. (2012)

Insect odorant binding proteins (OBPs) are the first components of the olfactory system to encounter and bind attractant and repellent odors emanating from various sources for presentation to olfactory receptors, which ...
Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: Comparison of chrysin and flavopiridol

Tsitsanou, K. E.; Hayes, J. M.; Keramioti, M.; Mamais, M.; Oikonomakos, N. G.; Kato, A.; Leonidas, D. D.; Zographos, S. E. (2013)

Flavonoids have been discovered as novel inhibitors of glycogen phosphorylase (GP), a target to control hyperglycemia in type 2 diabetes. To elucidate the mechanism of inhibition, we have determined the crystal structure ...