Πλοήγηση ανά Θέμα "Radiotherapy"
Αποτελέσματα 1-19 από 19
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Breast radiotherapy and early adverse cardiac effects. The role of serum biomarkers and strain echocardiography
(2019)Breast cancer radiotherapy has a clear benefit for both long-term survival and local recurrence rate. However, there is still much concern about the early radiation-induced heart toxicity. This article aimed to clarify the ... -
Clinical validation of the LKB model and parameter sets for predicting radiation-induced pneumonitis from breast cancer radiotherapy
(2006)The choice of the appropriate model and parameter set in determining the relation between the incidence of radiation pneumonitis and dose distribution in the lung is of great importance, especially in the case of breast ... -
Comparison of Two Radiotherapeutic Hypofractionated Schedules in the Application of Tumor Bed Boost
(2013)The application of the tumor bed boost by using 2 different hypofractionated planning techniques permit more efficient use of resources in hospitals. The evaluation of the radiation toxicity and the efficacy of the 2 ... -
Concurrent administration of liposomal doxorubicin improves the survival of patients with invasive bladder cancer undergoing hypofractionated accelerated radiotherapy (HypoARC)
(2011)Cisplatin-based radio-chemotherapy is an effective alternative to cystectomy. The position of cisplatin has been challenged by novel drugs, while altered radiotherapy fractionation is also tested against conventional ... -
Dose calculation optimization in intracranial stereotactic radiotherapy using implicit surface modeling
(2009)Intracranial Stereotactic radiotherapy / radiosurgery utilize fractioned dose delivery through multiple noncoplanar arcs to avoid harm of normal tissue. Proper positioning of the arcs in respect to avoid Organs at Risk ... -
An exploratory study of radiation dermatitis in breast cancer patients
(2018)Background/Aim: Radiation dermatitis is observed in 95% of breast cancer patients receiving radiotherapy. The aim of this study was to explore the correlation between protein expression in tumor cells and the risk of ... -
Field flatness and symmetry of photon beams: Review of the current recommendations
(2003)Flatness and symmetry are main parameters determining the quality of a photon beam produced by linear accelerators. The quality assurance in routine clinical practice of radiotherapy and consequently the treatment-outcome ... -
A free software for the evaluation and comparison of dose response models in clinical radiotherapy (DORES)
(2009)Purpose: The aim of this work was to develop a user-friendly and simple tool for fast and accurate estimation of Normal Tissue Complication Probabilities (NTCP) for several radiobiological models, which can be used as a ... -
High intratumoural accumulation of stealth® liposomal doxorubicin (Caelyx®) in glioblastomas and in metastatic brain tumours
(2000)The blood-brain barrier is a major obstacle for the chemotherapeutic drugs to effectively reach primary or secondary brain tumours, Stealth® liposomal drugs are highly accumulated in tumoural tissues. In the present study ... -
High resolution computed tomography findings on the lung of early breast-cancer patients treated by postoperative breast irradiation with a hypofractionated radiotherapy schedule
(2005)BACKGROUND: Hypofractionated breast radiotherapy (RT), although convenient for patients and health care systems, could have a negative impact on normal tissues such as lung. AIM: To evaluate radiation-induced lung toxicity ... -
Intraoperative radiation therapy on pancreatic cancer patients: a review of the literature
(2011)Pancreatic cancer is rarely curable, and the overall survival rate at 5 years is under 4%. This study aimed to assess the efficacy, effectiveness and safety of intraoperative radiation therapy (IORT) as treatment in ... -
Local intracerebral inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo
(2020)Glioblastoma multiforme (GBM) is the most severe primary brain cancer. Despite an aggressive treatment comprising surgical resection and radio/chemotherapy, patient's survival post diagnosis remains short. A limitation for ... -
Melanoma: The Radiotherapeutic point of view; review of the current literature
(2011)Surgery remains the mainstay of melanoma therapy at all sites. Melanoma is widely believed to be a radioresistant tumor, a misconception that has historically led to the limited use of RT for its treatment. We searched ... -
Molecular determinants of radiosensitivity in normal and tumor tissue: A bioinformatic approach
(2017)Although radiation therapy is a treatment of choice for cancer, a high percentage of patients develop adverse effects in normal tissue following radiotherapy, mainly, due to genetic factors. Notably, although it is established ... -
Monte carlo computational software and methods in radiation dosimetry
(2021)The fast developments and ongoing demands in radiation dosimetry have piqued the attention of many software developers and physicists to create powerful tools to make their experiments more exact, less expensive, more ... -
A new role of PET/CT for target delineation for radiotherapy treatment planning for head and neck carcinomas
(2012)Fluorine-18-fluorodeoxyglucose- positron emission tomography (F-18-FDG PET) in head and neck cancer patients is useful for staging, identification of macroscopic disease, detection of invaded lymph nodes and distant ... -
The potential role of radiation therapy in Bowen's disease: A review of the current literature
(2012)Background: Bowen's disease is a form of squamous cell carcinoma in situ that can be transformed into invasive squamous cell carcinoma and should be treated according to its anatomical position. The aim of this article is ... -
Primary extramammary invasive Paget's vulvar disease: What is the standard, what are the challenges and what is the future for radiotherapy?
(2016)Background: Primary invasive Extramammary Paget's vulvar disease is a rare tumor that is challenging to control. Wide surgical excision represents the standard treatment approach for Primary invasive Extramammary Paget's ... -
The use of radiobiological parameters and the evaluation of NTCP models. How do they affect the ability to estimate radiation induced complications?
(2009)Normal Tissue Complication Probability (NTCP) models currently used, provide a simplified representation of the clinical radiobiology since there are number of radiobiological mechanisms which affect the clinical outcome ...