Πλοήγηση ανά Θέμα "PHARMACOKINETICS"
Αποτελέσματα 1-9 από 9
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Activity of Tigecycline in Combination with Colistin, Meropenem, Rifampin, or Gentamicin against KPC-Producing Enterobacteriaceae in a Murine Thigh Infection Model
(2013)Limited antimicrobials remain active for treating severe infections due to KPC-producing pathogens, and optimal regimens have not been established. In murine thigh infections caused by nine KPC-producing clinical strains ... -
Concentrations of clindamycin hydrochloride in homogenates of normal dog skin when administered at two oral dosage regimens
(2013)Background: Clindamycin is frequently used for the treatment of bacterial pyoderma. Objective: To compare the pharmacokinetics of clindamycin in whole skin homogenates of normal dogs when administered orally at two dosage ... -
The effects of the short-term administration of low therapeutic doses of anti-COX-2 agents on the healing of fractures - An experimental study in rabbits
(2007)We have evaluated the effect of the short-term administration of low therapeutic doses of modern COX-2 inhibitors on the healing of fractures. A total of 40 adult male New Zealand rabbits were divided into five groups. A ... -
Elimination profiles of flurbiprofen and its metabolites in equine urine for doping analysis
(2001)Flurbiprofen and its main acidic metabolites were detected in equine urine after a single-dose administration of 500 mg flurbiprofen to two 2.5-3.5-years-old mares, in order to be used in equine doping control routine ... -
In vitro activity of dietary flavonol congeners against human cancer cell lines
(2012)Flavonoids have physiological activity and a variety of pharmacological properties, including anticancer activity in vitro, but structure-anticancer activity relationships are unclear. The objectives of this work were to ... -
Peripheral distribution of amoxicillin in sheep and influence of local inflammation
(2010)The pharmacokinetics of amoxicillin (AMX) in blood serum (SBS) and tissue cage fluid (TCF) was studied in sheep. Four tissue cages, prepared from silicone rubber tubing, were subcutaneously inserted in the neck area (two ... -
Poor bioavailability of oxytetracycline in sharpsnout sea bream Diplodus puntazzo
(2004)The pharmacokinetics of oxytetracycline (OTC) were investigated following single intravascular injection (40 mg/kg) in sharpsnout sea bream (90 g) at 19 degreesC. The distribution half-life (t(1/2alpha)) and the elimination ... -
Simple and Reliable HPLC Method for the Monitoring of Methotrexate in Osteosarcoma Patients
(2014)Methotrexate (MTX) is a dihydrofolate reductase inhibitor that is used for the treatment of tumors and autoimmune diseases. Several automated binding assays are used in clinical practice and numerous chromatographic methods ...