Browsing by Subject "NITRIC-OXIDE"
Now showing items 1-20 of 22
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2-Oxoglutarate-dependent oxygenases control hepcidin gene expression
(2008)Background/Aims: Hepcidin is a liver-produced hormone that regulates systemic iron homeostasis. Hepcidin expression is stimulated upon iron overload or inflammation while iron deficiency, anemia and tissue hypoxia are ... -
Airway responsiveness: role of inflammation, epithelium damage and smooth muscle tension
(1999)THE purpose of this study was the effect of epithelium damage on mechanical responses of airway smooth muscles under different resting tension. We performed acetylcholine (ACh) (10(-5) M)-induced contraction on tracheal ... -
Biomarkers Obtained by Non-Invasive Methods in Patients with COPD: Where do we Stand, what do we Expect?
(2009)Recently, there has been widespread interest in the use of non-invasive methods for the assessment of airway inflammation in a variety of lung diseases including chronic obstructive pulmonary disease ( COPD). Sputum induction ... -
Cobalt induces hypoxia-inducible factor-1 alpha expression in airway smooth muscle cells by a reactive oxygen species- and PI3K-dependent mechanism
(2004)Cobalt can mimic hypoxia and has been implicated as a cause of lung defects. However, the effect of cobalt on airway smooth muscle (ASM) cells has not been analyzed in detail. In this article, we use primary cultures of ... -
Connection between Telomerase Activity in PBMC and Markers of Inflammation and Endothelial Dysfunction in Patients with Metabolic Syndrome
(2012)Metabolic syndrome (MS) is a constellation of metabolic derangements associated with vascular endothelial dysfunction and oxidative stress and is widely regarded as an inflammatory condition, accompanied by an increased ... -
Effect of an OT antagonist on the control of the midcycle LH surge in women
(2009)P>Objective Data in women regarding the role of OT in LH secretion during the LH surge are conflicting. As in previous studies blood samples for LH measurements were taken infrequently, we re-examined this matter in women ... -
Effects of scopolamine and L-NAME on rats' performance in the object location test
(2007)The object location task is a new procedure evaluating spatial memory abilities in the rat. The aim of the present study was to characterize this behavioural paradigm by pharmacologic means. For this purpose, the effects ... -
Evidence for non genomic action of 17 beta estradiol on transepithelial resistance of human fetal membranes
(2011)Background: The role of hormones in the transport mechanisms of human fetal membranes in pregnancy is unclear. Estrogens are essential hormones in pregnancy and they play an important role in the ion transport via membranes. ... -
Exhaled breath condensate in patients with asthma: implications for application in clinical practice
(2008)Exhaled breath condensate (EBC) analysis, a rather appealing and promising method, can be used to evaluate conveniently and non-invasively a wide range of molecules from the respiratory tract, and to understand better the ... -
Interplay between protein carbonylation and nitrosylation in plants
(2013)ROS and reactive nitrogen species (RNS) are key regulators of redox homeostasis in living organisms including plants. As control of redox homeostasis plays a central function in plant biology, redox proteomics could help ... -
Investigation of in vivo toxicity of hydroxylamine sulfate and the efficiency of intoxication treatment by alpha-tocopherol acetate and methylene blue
(2013)Objectives: Investigation of hydroxylamine sulfate toxicity mechanism in vivo and estimation of alpha-tocopherol acetate and methylene blue efficiency in poisoning treatments. Methods: In vivo experiments were conducted ... -
Leptin, Adiponectin, and Ghrelin Levels in Female Patients with Asthma during Stable and Exacerbation Periods
(2013)Objective. The mechanisms underlying the relationship between obesity and asthma have not been fully established. Data in the literature suggest that adipose tissue-derived hormones may be implicated. However, no definite ... -
Local infusion of ascorbate augments NO-dependent cutaneous vasodilatation during intense exercise in the heat
(2015)Nitric oxide (NO)-dependent cutaneous vasodilatation is reportedly diminished during exercise performed at a high (700W) relative to moderate (400W) rate of metabolic heat production. The present study evaluated whether ... -
Molsidomine antagonizes L-NAME-induced acquisition deficits in a recognition memory task in the rat
(2003)The present study was designed to investigate the role of nitric oxide (NO) on the acquisition of a recognition memory, task in the rat. For this purpose, the effects on memory exerted by pre-training administration of the ... -
Oxidative stress and inflammatory markers in the exhaled breath condensate of children with OSA
(2012)Obstructive sleep apnea (OSA) in children has been associated with systemic inflammation and oxidative stress. Limited evidence indicates that pediatric OSA is associated with oxidative stress and inflammation in the airway. ... -
Oxidative stress responses in older men during endurance training and detraining
(2004)Purpose: Aging is associated with increased oxidative stress, whereas systematic exercise training has been shown to improve quality of life and functional performance of the aged. This study aimed to evaluate responses ...