Πλοήγηση ανά Συγγραφέα "Moutselos, K."
Αποτελέσματα 1-8 από 8
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Building in-silico pathway SBML models from heterogeneous sources
(2008)The recent revolutionary developments concerning the high throughput (-omics) measuring techniques in life sciences is expediting the way for the development of in silico models envisioning the Systems biology perspective ... -
Delineation and interpretation of gene networks towards their effect in cellular physiology- a reverse engineering approach for the identification of critical molecular players, through the use of ontologies
(2010)Exploiting ontologies, provides clues regarding the involvement of certain molecular processes in the cellular phenotypic manifestation. However, identifying individual molecular actors (genes, proteins, etc.) for targeted ... -
Gene prioritization for inference of robust composite diagnostic signatures in the case of melanoma
(2013)An integrated dataset originating from multi-modal datasets can be used to target underlying causal biological actions that through a systems level process trigger the development of a disease. In this study, we use an ... -
GOrevenge: A Novel Generic Reverse Engineering Method for the Identification of Critical Molecular Players, Through the Use of Ontologies
(2011)The ever-increasing use of ontologies in modern biological analysis and interpretation facilitates the understanding of the cellular procedures, their hierarchical organization, and their potential interactions at a system's ... -
Heterogeneous data fusion and selection in high-volume molecular and imaging datasets
(2012)In this work, two disparate datasets, concerning the study of the same physiological type of cutaneous melanoma but derived from different donors, one of image (dermatoscopy) and the other of molecular (trascriptomic ... -
Inference of a robust diagnostic signature in the case of melanoma: Gene selection by information gain and gene ontology tree exploration
(2013)Integrated datasets originating from multi-modal data can be used towards the identification of causal biological actions that through a systems level process trigger the development of a disease. We use, here, an integrated ... -
Integration of High-Volume Molecular and Imaging Data for Composite Biomarker Discovery in the Study of Melanoma
(2014)In this work the effects of simple imputations are studied, regarding the integration of multimodal data originating from different patients. Two separate datasets of cutaneous melanoma are used, an image analysis (dermoscopy) ... -
KEGGconverter: a tool for the in-silico modelling of metabolic networks of the KEGG Pathways database
(2009)Background: The KEGG Pathway database is a valuable collection of metabolic pathway maps. Nevertheless, the production of simulation capable metabolic networks from KEGG Pathway data is a challenging complicated work, ...