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Πλοήγηση ανά Θέμα 
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Πλοήγηση ανά Θέμα "MTHFR"

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Αποτελέσματα 1-11 από 11

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    • Thumbnail

      Association of methylenetetrahydrofolate reductase (MTHFR) polymorphisms with genetic susceptibility to gastric cancer: a meta-analysis 

      Zintzaras, E. (2006)
      To clarify the influence of MTHFR C677T and A1298C polymorphisms on gastric cancer (GC), a meta-analysis of eight case-control studies (1,584/2,785 cases/controls) was carried out. Overall, there was moderate heterogeneity ...
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      Evidence of Association Between Methylenetetrahydrofolate Reductase Gene and Susceptibility to Breast Cancer: A Candidate-Gene Association Study in a South-Eastern European Population 

      Papandreou, C. N.; Doxani, C.; Zdoukopoulos, N.; Vlachostergios, P. J.; Hatzidaki, E.; Bakalos, G.; Ziogas, D. C.; Koufakis, T.; Zintzaras, E. (2012)
      The methylenetetrahydrofolate reductase (MTHFR) gene has been proposed as a candidate gene for breast cancer (BC). However, the specific role of MTHFR polymorphisms and haplotypes has not been fully clarified and replicated. ...
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      Genetic variants of homocysteine/folate metabolism pathway and risk of inflammatory bowel disease: a synopsis and meta-analysis of genetic association studies 

      Zintzaras, E. (2010)
      A synopsis and meta-analysis of studies that investigated the association between genetic variants involved in the homocysteine/folate metabolism pathway and risk of inflammatory bowel disease (IBD) were conducted. Four ...
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      Maternal gene polymorphisms involved in folate metabolism and risk of Down syndrome offspring: a meta-analysis 

      Zintzaras, E. (2007)
      Studies investigating the association between gene polymorphisms involved in homocysteine/folate metabolism and Down syndrome (DS) have reported contradictory or inconclusive results. A meta-analysis of 11 case-control ...
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      A meta-analysis of genotypes and haplotypes of methylenetetrahydrofolate reductase gene polymorphisms in acute lymphoblastic leukemia 

      Zintzaras, E.; Koufakis, T.; Ziakas, P. D.; Rodopoulou, P.; Giannouli, S.; Voulgarelis, M. (2006)
      A meta-analysis of case-control studies that investigated the association between the C677T and/or A1298C polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and acute lymphoblastic leukemia (ALL) was ...
    • Thumbnail

      Methylenetetrahydrofolate reductase gene and susceptibility to breast cancer: a meta-analysis 

      Zintzaras, E. (2006)
      The methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms have been linked to the risk of developing breast cancer. A meta-analysis of 18 case-control studies investigating the association between the C677T and ...
    • Thumbnail

      Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy: a meta-analysis 

      Zintzaras, E.; Uhlig, K.; Koukoulis, G. N.; Papathanasiou, A. A.; Stefanidis, I. (2007)
      Investigations into the association between diabetic nephropathy (DN) and MTHFR C677T gene polymorphism in several case-control studies has yielded contradictory results. To shed light on these inconclusive findings, a ...
    • Thumbnail

      MTHFR gene polymorphisms and response to chemotherapy in colorectal cancer: a meta-analysis 

      Zintzaras, E.; Ziogas, D. C.; Kitsios, G. D.; Papathanasiou, A. A.; Lau, J.; Raman, G. (2009)
      Aims: Pharmacogenetic studies investigating the relationship between MTHFR gene polymorphisms and response to fluorouracil-based chemotherapy in patients with colorectal cancer have produced inconclusive results. In an ...
    • Thumbnail

      The relationship between C677T methylenetetrahydrofolate reductase gene polymorphism and retinopathy in type 2 diabetes: a meta-analysis 

      Zintzaras, E.; Chatzoulis, D. Z.; Karabatsas, C. H.; Stefanidis, I. (2005)
      The association between retincipathy in type 2 diabetes [diabetic retinopathy (DR)] and the C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene has been investigated in several case-control studies. ...
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      The role of MTHFR gene in multiple myeloma 

      Zintzaras, E.; Giannouli, S.; Rodopoulou, P.; Voulgarelis, M. (2008)
      Case-control studies investigating associations between multiple myeloma (MM) and the C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) have provided controversial results. In an attempt to ...
    • Thumbnail

      Variants of the MTHFR gene and susceptibility to acute lymphoblastic leukemia in children: A synthesis of genetic association studies 

      Zintzaras, E.; Doxani, C.; Rodopoulou, P.; Bakalos, G.; Ziogas, D. C.; Ziakas, P.; Voulgarelis, M. (2012)
      Background: Acute lymphoblastic leukemia (ALL) is a complex disease with genetic background. The genetic association studies (GAS) that investigated the association between ALL and the MTHFR C677T and A1298C gene variants ...
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