Πλοήγηση ανά Συγγραφέα "Kostopoulou, F."
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Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis
Kostopoulou, F.; Gkretsi, V.; Malizos, K. N.; Iliopoulos, D.; Oikonomou, P.; Poultsides, L.; Tsezou, A. (2012)Background: Recent studies have implied that osteoarthritis (OA) is a metabolic disease linked to deregulation of genes involved in lipid metabolism and cholesterol efflux. Sterol Regulatory Element Binding Proteins (SREBPs) ... -
DNA methylation regulates sclerostin (SOST) expression in osteoarthritic chondrocytes by bone morphogenetic protein 2 (BMP-2) induced changes in Smads binding affinity to the CpG region of SOST promoter
Papathanasiou, I.; Kostopoulou, F.; Malizos, K. N.; Tsezou, A. (2015)Introduction: Sclerostin (SOST), a soluble antagonist of Wnt signaling, is expressed in chondrocytes and contributes to chondrocytes' hypertrophic differentiation; however its role in osteoarthritis (OA) pathogenesis is ... -
IMPAIRED EXPRESSION OF GENES INVOLVED IN REVERSE CHOLESTEROL TRANSPORT IN HUMAN OSTEOARTHRITIC CHONDROCYTES: BENEFICIAL EFFECT OF LXR AGONIST TREATMENT
Simopoulou, T.; Malizos, K. N.; Kostopoulou, F.; Tsezou, A. (2010) -
Influence of Interleukin 1 alpha (IL-1 alpha), IL-4, and IL-6 Polymorphisms on Genetic Susceptibility to Chronic Osteomyelitis
Tsezou, A.; Poultsides, L.; Kostopoulou, F.; Zintzaras, E.; Satra, M.; Kitsiou-Tzeli, S.; Malizos, K. N. (2008)The association between cytokine gene polymorphisms and chronic osteomyelitis was investigated in order to determine whether genetic variability in cytokine genes predisposes to osteomyelitis susceptibility. Significant ... -
MICRORNA-33A REGULATES CHOLESTEROL SYNTHESIS AND CHOLESTEROL EFFLUX RELATED GENES IN OSTEOARTHRITIC CHONDROCYTES
Kostopoulou, F.; Malizos, K. N.; Papathanasiou, I.; Tsezou, A. (2015) -
MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes
Kostopoulou, F.; Malizos, K. N.; Papathanasiou, I.; Tsezou, A. (2015)Introduction: Several studies have shown that osteoarthritis (OA) is strongly associated with metabolism-related disorders, highlighting OA as the fifth component of the metabolic syndrome (MetS). On the basis of our ... -
Quantitative Proteomics of Hypertrophic Chondrocytes in Osteoarthritis
Tsolis, K.; Papathanasiou, I.; Kostopoulou, F.; Gkretsi, V.; Mpei, E. S.; Kalatzaki, K.; Zerbakis, M.; Malizos, K.; Tsezou, A.; Economou, A. (2014)