Browsing by Author "Hadjigeorgiou, G. M."
Now showing items 1-20 of 106
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A1-antichymotrypsin gene polymorphism and primary intracerebral hemorrhage (ICH)
Dardiotis, E.; Dardioti, M.; Aggelakis, K.; Komnos, A.; Noulas, G.; Paterakis, K.; Tasiou, A.; Papadimitriou, A.; Hadjigeorgiou, G. M. (2006) -
Absence of aprataxin gene mutations in a Greek cohort with sporadic early onset ataxia and normal GAA triplets in frataxin gene
Daiou, C.; Christodoulou, K.; Xiromerisiou, G.; Panas, M.; Dardiotis, E.; Kladi, A.; Speletas, M.; Ntaios, G.; Papadimitriou, A.; Germenis, A.; Hadjigeorgiou, G. M. (2010)Phenotype of patients with the aprataxin gene mutation varies and according to previous studies, screening of aprataxin gene could be useful, once frataxin gene mutation is excluded in patients with normal GAA expansion ... -
Absence of linkage to chromosomes 6q and 16p in a Greek population with knee osteoarthritis
Tsezou, A.; Karachalios, T.; Fytili, P.; Giannatou, E.; Christodoulou, K.; Hadjigeorgiou, G. M.; Malizos, K. N. (2006)Osteoarthritis (OA) is a common age-related debilitating disease of the joints characterized by degeneration of the articular cartilage which leads to joint pain, discomfort, and immobility. Several risk factors have been ... -
Aerobic exercise training ameliorates RLS symptoms and improves functional capacity in patients receiving dialysis therapy
Sakkas, G. K.; Hadjigeorgiou, G. M.; Karatzaferi, C.; Giannaki, C. D.; Maridaki, M.; Roundas, C.; Vlychou, M.; Liakopoulos, V.; Stefanidis, I. (2007) -
Alpha-1 antichymotrypsin gene signal peptide A/T polymorphism and primary intracerebral hemorrhage
Dardiotis, E.; Hadjigeorgiou, G. M.; Dardioti, M.; Scarmeas, N.; Paterakis, K.; Aggelakis, K.; Komnos, A.; Tasiou, A.; Xiromerisiou, G.; Gabranis, I.; Zintzaras, E.; Papadimitriou, A.; Karantanas, A. (2008)Background/Aims: Alpha-1 antichymotrypsin (ACT), a serine proteinase inhibitor, has been implicated in vascular pathology. The TT genotype of the ACT signal peptide A/T polymorphism has been reported to confer susceptibility ... -
Angiotensin converting enzyme (ACE) I/D gene polymorphism and primary intracerebral hemorrhage (ICH)
Dardiotis, E.; Dardioti, M.; Aggelakis, K.; Komnos, A.; Noulas, G.; Paterakis, K.; Tasiou, A.; Papadimitriou, A.; Hadjigeorgiou, G. M. (2006) -
Angiotensin-converting enzyme tag single nucleotide polymorphisms in patients with intracerebral hemorrhage
Dardiotis, E.; Jagiella, J.; Xiromerisiou, G.; Dardioti, M.; Vogiatzi, C.; Urbanik, A.; Paterakis, K.; Komnos, A.; Fountas, K. N.; Slowik, A.; Hadjigeorgiou, G. M. (2011)Objectives Studies investigating the association between angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and the risk of intracerebral hemorrhage (ICH) have provided conflicting results. Moreover, ... -
AQP4 Tag Single Nucleotide Polymorphisms in Patients with Traumatic Brain Injury
Dardiotis, E.; Paterakis, K.; Tsivgoulis, G.; Tsintou, M.; Hadjigeorgiou, G. F.; Dardioti, M.; Grigoriadis, S.; Simeonidou, C.; Komnos, A.; Kapsalaki, E.; Fountas, K.; Hadjigeorgiou, G. M. (2014)Accumulating evidence suggests that the extent of brain injury and the clinical outcome after traumatic brain injury (TBI) are modulated, to some degree, by genetic variants. Aquaporin-4 (AQP4) is the predominant water ... -
Assessment of Parkinson's disease risk loci in Greece
Kara, E.; Xiromerisiou, G.; Spanaki, C.; Bozi, M.; Koutsis, G.; Panas, M.; Dardiotis, E.; Ralli, S.; Bras, J.; Letson, C.; Edsall, C.; Pliner, H.; Arepalli, S.; Kalinderi, K.; Fidani, L.; Bostantjopoulou, S.; Keller, M. F.; Wood, N. W.; Hardy, J.; Houlden, H.; Stefanis, L.; Plaitakis, A.; Hernandez, D.; Hadjigeorgiou, G. M.; Nalls, M. A.; Singleton, A. B. (2014)Genome-wide association studies (GWAS) have been shown to be a powerful approach to identify risk loci for neurodegenerative diseases. Recent GWAS in Parkinson's disease (PD) have been successful in identifying numerous ... -
Assessment of the Relative Effectiveness and Tolerability of Treatments of Type 2 Diabetes Mellitus: A Network Meta-analysis
Zintzaras, E.; Miligkos, M.; Ziakas, P.; Balk, E. M.; Mademtzoglou, D.; Doxani, C.; Mprotsis, T.; Gowri, R.; Xanthopoulou, P.; Mpoulimari, I.; Kokkali, C.; Dimoulou, G.; Rodopolou, P.; Stefanidis, I.; Kent, D. M.; Hadjigeorgiou, G. M. (2014)Purpose: The relative effectiveness and tolerability of treatments for type 2 diabetes mellitus (T2DM) is not well understood because few randomized, controlled trials (RCTs) have compared these treatments directly. The ... -
Association between AKT1 gene and Parkinson's disease: A protective haplotype
Xiromerisiou, G.; Hadjigeorgiou, G. M.; Papadimitriou, A.; Katsarogiannis, E.; Gourbali, V.; Singleton, A. B. (2008)Variation in AKT1 has been associated with schizophrenia, bipolar disease and type 11 diabetes. The aim of the present study was to investigate the potential role of variability within AKT1 as a risk factor for Parkinson's ... -
Association Between the Interleukin-1 beta Gene (IL1B) C-511T Polymorphism and the Risk of Diabetic Nephropathy in Type 2 Diabetes: A Candidate-Gene Association Study
Stefanidis, I.; Kreuer, K.; Dardiotis, E.; Arampatzis, S.; Eleftheriadis, T.; Hadjigeorgiou, G. M.; Zintzaras, E.; Mertens, P. R. (2014)Variants of the interleukin-1 beta gene (IL1B) are implicated in the development of diabetic nephropathy (DN). The present candidate-gene association study was conducted to investigate the association between the IL1B ... -
Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study
Ross, O. A.; Soto-Ortolaza, A. I.; Heckman, M. G.; Aasly, J. O.; Abahuni, N.; Annesi, G.; Bacon, J. A.; Bardien, S.; Bozi, M.; Brice, A.; Brighina, L.; Van Broeckhoven, C.; Carr, J.; Chartier-Harlin, M. C.; Dardiotis, E.; Dickson, D. W.; Diehl, N. N.; Elbaz, A.; Ferrarese, C.; Ferraris, A.; Fiske, B.; Gibson, J. M.; Gibson, R.; Hadjigeorgiou, G. M.; Hattori, N.; Ioannidis, J. P. A.; Jasinska-Myga, B.; Jeon, B. S.; Kim, Y. J.; Klein, C.; Kruger, R.; Kyratzi, E.; Lesage, S.; Lin, C. H.; Lynch, T.; Maraganore, D. M.; Mellick, G. D.; Mutez, E.; Nilsson, C.; Opala, G.; Park, S. S.; Puschmann, A.; Quattrone, A.; Sharma, M.; Silburn, P. A.; Sohn, Y. H.; Stefanis, L.; Tadic, V.; Theuns, J.; Tomiyama, H.; Uitti, R. J.; Valente, E. M.; van de Loo, S.; Vassilatis, D. K.; Vilarino-Guell, C.; White, L. R.; Wirdefeldt, K.; Wszolek, Z. K.; Wu, R. M.; Farrer, M. J.; Genetic Epidemiology Parkinson's, D. (2011)Background The leucine-rich repeat kinase 2 gene (LRRK2) harbours highly penetrant mutations that are linked to familial parkinsonism. However, the extent of its polymorphic variability in relation to risk of Parkinson's ... -
Association of paraoxonase 1 gene polymorphisms with risk of Parkinson's disease: a meta-analysis
Zintzaras, E.; Hadjigeorgiou, G. M. (2004)Paraoxonase1 (PON1) gene polymorphisms were implicated as risk factors for Parkinson's disease (PD), but the results of case-control studies that investigated these associations were controversial. In order to provide an ... -
Association of tau haplotype-tagging polymorphisms with Parkinson's disease in diverse ethnic Parkinson's disease cohorts
Fung, H. C.; Xiromerisiou, G.; Gibbs, J. R.; Wu, Y. R.; Eerola, J.; Gourbali, V.; Hellstrom, O.; Chen, C. M.; Duckworth, J.; Papadimitriou, A.; Tienari, P. J.; Hadjigeorgiou, G. M.; Hardy, J.; Singleton, A. B. (2006)Background: The overlap in the clinical and pathological features of tauopathies and synucleinopathies raises the possibility that the tau protein may be important in Parkinson's disease (PD) pathogenesis. Several MAPT ... -
Autoantibodies to alpha-synuclein in inherited Parkinson's disease
Papachroni, K. K.; Ninkina, N.; Papapanagiotou, A.; Hadjigeorgiou, G. M.; Xiromerisiou, G.; Papadimitriou, A.; Kalofoutis, A.; Buchman, V. L. (2007)Neurodegeneration in Parkinson's disease (PD) is accompanied by a local immune reaction in the affected brain regions. It is well established that alpha-synuclein is directly implicated in the pathogenesis of PD. Development ... -
BDNF tagging polymorphisms and haplotype analysis in sporadic Parkinson's disease in diverse ethnic groups
Xiromerisiou, G.; Hadjigeorgiou, G. M.; Eerola, J.; Fernandez, H. H.; Tsimourtou, V.; Mandel, R.; Hellstrom, O.; Gwinn-Hardy, K.; Okun, M. S.; Tienari, P. J.; Singleton, A. B. (2007)Experimental and clinical data suggest that genetic variations in brain-derived neurotrophic factor (BDNF) gene may affect risk for Parkinson's disease (PD). We performed a case-control association analysis of BDNF in three ... -
Brain MRI and proton MRS findings in infants and children with respiratory chain defects
Dinopoulos, A.; Cecil, K. M.; Schapiro, M. B.; Papadimitriou, A.; Hadjigeorgiou, G. M.; Wong, B.; DeGrauw, T.; Egelhoff, J. C. (2005)Objective: The aim of this study is to describe neuroimaging patterns in children with respiratory chain (RC) defects using magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (MRS) and to assess ... -
Clinical trials in restless legs syndrome - Recommendations of the European RLS study group (EURLSSG)
Trenkwalder, C.; Kohnen, R.; Allen, R. P.; Benes, H.; Ferini-Strambi, L.; Garcia-Borreguero, D.; Hadjigeorgiou, G. M.; Happe, S.; Hogl, B.; Hornyak, M.; Klein, C.; Nass, A.; Montagna, P.; Oertel, W. H.; O'Keeffe, S.; Paulus, W.; Poewe, W.; Provini, F.; Pramstaller, P. P.; Sieminski, M.; Sonka, K.; Stiasny-Kolster, K.; de Weerd, A.; Wetter, T. C.; Winkelmann, J.; Zucconi, M. (2007)The European Restless Leas Syndrome (RLS) Study Group (EURLSSG) is an association of European RLS experts who are actively involved in RLS research. A major aim of the Study Group is the development and continuous improvement ... -
Cognitive impairment in heart failure
Dardiotis, E.; Giamouzis, G.; Mastrogiannis, D.; Vogiatzi, C.; Skoularigis, J.; Triposkiadis, F.; Hadjigeorgiou, G. M. (2012)Cognitive impairment (CI) is increasingly recognized as a common adverse consequence of heart failure (HF). Although the exact mechanisms remain unclear, microembolism, chronic or intermittent cerebral hypoperfusion, and/or ...