Πλοήγηση ανά Συγγραφέα "Georgoulias, P."
Αποτελέσματα 1-20 από 72
-
Alzheimer's Disease: SPECT and PET Tracers for Beta-Amyloid Imaging
(2010)The definite diagnosis of Alzheimer's disease (AD) is based on the detection of beta amyloid (A beta) plaques and neurofibrillary tangles (NFTs) - which are the pathological hallmarks of the disease- in the postmortem ... -
Association between habitual physical activity and brown adipose tissue activity in individuals undergoing PET-CT scan
(2015)ObjectiveAugmented brown adipose tissue (BAT) mass and activity lead to higher basic metabolic rate which is beneficial against obesity. Our aim was to investigate whether habitual (i.e. usual weekly participation) physical ... -
Association of Bone Mineral Density, Parameters of Bone Turnover, and Body Composition in Patients With Chronic Obstructive Pulmonary Disease
(2012)Patients with chronic obstructive pulmonary disease (COPD) often develop osteoporosis. Many hormones regulate bone metabolism and body composition, and some of them are affected in COPD patients vs controls. In 46 COPD ... -
The Association of Metabolic Syndrome with Adipose Tissue Hormones and Insulin Resistance in Patients with COPD without Co-morbidities
(2011)Chronic obstructive pulmonary disease (COPD) and metabolic syndrome represent common causes of morbidity and mortality in ageing populations. The effect of the co-existence of COPD and metabolic syndrome on adipose tissue ... -
Attenuating activity of the ovary on LH response to GnRH during the follicular phase of the cycle
(2014)Objective Oestradiol sensitizes the pituitary to GnRH, while gonadotrophin surge attenuating factor (GnSAF) may oppose this action. Using the LH response to GnRH during treatment with FSH as an in vivo bioassay for GnSAF, ... -
Baseline Insulin-Like Growth Factor-I Plasma Levels, Systemic Inflammation, Weight Loss and Clinical Outcome in Metastatic Non-Small Cell Lung Cancer Patients
(2011)Background: Cancer patients frequently suffer from weight loss and systemic inflammation in the context of advanced disease, which is related to adverse outcome. Insulin-like growth factor (IGF)-I is an anabolic molecule ... -
Blockage of ghrelin-induced prolactin secretion in women by bromocriptine
(2010)Objective: To investigate the effect of bromocriptine on ghrelin-induced PRL secretion in women. Design: Longitudinal study. Setting: University hospital. Patient(s): Ten healthy, normally cycling women. Intervention(s): ... -
Brain perfusion SPECT with 99mTC-ECD and serum neuron-specific enolase in patients with spontaneous subarachnoid haemorrhage and clinical vasospasm
(2006)Aim: To estimate the association between single photon emission computed tomography (SPECT) imaging and neuro-specific enolase (NSE) serum level measurement in patients with subarachnoid haemorrhage (SAH) and also to present ... -
Brain Perfusion SPECT with Brodmann Areas Analysis in Differentiating Frontotemporal Dementia Subtypes
(2014)Despite the known validity of clinical diagnostic criteria, significant overlap of clinical symptoms between Frontotemporal dementia (FTD) subtypes exists in several cases, resulting in great uncertainty of the diagnostic ... -
CER1 gene variations associated with bone mineral density, bone markers, and early menopause in postmenopausal women
(2013)Background: Osteoporosis has a multifactorial pathogenesis characterized by a combination of low bone mass and increased fragility. In our study, we focused on the effects of polymorphisms in CER1 and DKK1 genes, recently ... -
Clinical Evaluation of Brain Perfusion SPECT with Brodmann Areas Mapping in Early Diagnosis of Alzheimer's Disease
(2015)Early diagnosis of Alzheimer's disease (AD) based on clinical criteria alone may be problematic, while current and future treatments should be administered earlier in order to be more effective. Thus, various disease ... -
Clinical significance of serum adipokines levels in lung cancer
(2013)Adipokines have a significant effect on metabolism, immunoinflammatory responses as well as on carcinogenesis; therefore, we aimed at evaluating their potential predictive and prognostic significance in lung cancer. Eighty ... -
Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells
(2013)Hypoxia-inducible factors (HIFs) are transcriptional regulators that mediate the cellular response to low oxygen. Although HIF-1 is usually considered as the principal mediator of hypoxic adaptation, several tissues and ... -
Cytolytic T-cell response against Epstein-Barr virus in lung cancer patients and healthy subjects
(2010)Background: This study aimed to examine whether EBV seropositive patients with lung cancer have an altered virus-specific CTL response, as compared to age-matched healthy controls and whether any variation in this response ... -
Development and evaluation of QSPECT open-source software for the iterative reconstruction of SPECT images
(2010)Objective In this study open-source software (QSPECT) suitable for the iterative reconstruction of single-photon emission computed tomography (SPECT) data is presented. QSPECT implements maximum likelihood expectation ... -
Early detection of melanoma with the combined use of acoustic microscopy, infrared reflectance and Raman spectroscopy
(2015)Malignant melanoma is a form of skin cancer, with increasing incidence worldwide. Early diagnosis is crucial for the prognosis and treatment of the disease. The objective of this study is to develop a novel animal model ... -
Effect of Anti-Mullerian hormone (AMH) and bone morphogenetic protein 15 (BMP-15) on steroidogenesis in primary-cultured human luteinizing granulosa cells through Smad5 signalling
(2015)To determine if there is any effect of AMH and BMP-15 on estradiol and progesterone production from primary-cultured human luteinizing granulosa cells, to delineate what is the effect of FSH on their actions and which are ... -
Effect of ghrelin and metoclopramide on prolactin secretion in normal women
(2011)Background: Administration of ghrelin to women stimulates the secretion of PRL but the mechanism is not known. Aim: The aim of the study was to investigate the effect of the dopamine receptor blocker, metoclopramide, on ...