Πλοήγηση ανά Συγγραφέα "Doxani, C."

Assessing the relative effectiveness and tolerability of treatments in small cell lung cancer: A network meta-analysis

Bakalos, G.; Miligkos, M.; Doxani, C.; Mpoulimari, I.; Rodopoulou, P.; Zintzaras, E. (2013)

Background: The combination of Cisplatin plus Etoposide (EP) is currently the standard treatment for small cell lung cancer (SCLC). However, a large number of alternative treatments (monotherapies and combinations) have ...

Assessment of the Relative Effectiveness and Tolerability of Treatments of Type 2 Diabetes Mellitus: A Network Meta-analysis

Zintzaras, E.; Miligkos, M.; Ziakas, P.; Balk, E. M.; Mademtzoglou, D.; Doxani, C.; Mprotsis, T.; Gowri, R.; Xanthopoulou, P.; Mpoulimari, I.; Kokkali, C.; Dimoulou, G.; Rodopolou, P.; Stefanidis, I.; Kent, D. M.; Hadjigeorgiou, G. M. (2014)

Purpose: The relative effectiveness and tolerability of treatments for type 2 diabetes mellitus (T2DM) is not well understood because few randomized, controlled trials (RCTs) have compared these treatments directly. The ...

Bone mineral density and genetic markers involved in three connected pathways (focal adhesion, actin cytoskeleton regulation and cell cycle): The CUMAGAS-BMD information system

Zintzaras, E.; Doxani, C.; Ziogas, D. C.; Mprotsis, T.; Rodopoulou, P.; Karachalios, T. (2011)

The focal adhesion, the actin cytoskeleton and cell-cycle are connected pathways and their genes are implicated in the pathogenesis of low BMD. Data from 211 studies that investigated the association between BMD and gene ...

THE CUMAGAS-OSTEO DATABASE INFORMATION SYSTEM FOR CATALOGUING AND META-ANALYZING GENETIC ASSOCIATION STUDIES IN OSTEOPOROSIS: DEMONSTRATION USING GENES IN FOCAL ADHESION PATHWAY

Doxani, C.; Zintzaras, E.; Karahalios, T.; Ziogas, D.; Kastanis, A.; Dahabre, I.; Papathanasiou, A. (2010)

Evidence of Association Between Methylenetetrahydrofolate Reductase Gene and Susceptibility to Breast Cancer: A Candidate-Gene Association Study in a South-Eastern European Population

Papandreou, C. N.; Doxani, C.; Zdoukopoulos, N.; Vlachostergios, P. J.; Hatzidaki, E.; Bakalos, G.; Ziogas, D. C.; Koufakis, T.; Zintzaras, E. (2012)

The methylenetetrahydrofolate reductase (MTHFR) gene has been proposed as a candidate gene for breast cancer (BC). However, the specific role of MTHFR polymorphisms and haplotypes has not been fully clarified and replicated. ...

FDG-PET for detecting local tumor recurrence of ablated liver metastases: a diagnostic meta-analysis

Poulou, L. S.; Ziakas, P. D.; Ziogas, D. C.; Doxani, C.; Xyla, V.; Vakrinos, G.; Voulgarelis, M.; Thanos, L. (2012)

Context: Scanty reports have focused on FDG-PET after radiofrequency ablation (RFA), for recurrence of hepatic metastases. Objective: To assess FDG-PET diagnostic accuracy on detection of recurrent hepatic lesions. Methods: ...

MDR1 mRNA expression and MDR1 gene variants as predictors of response to chemotherapy in patients with acute myeloid leukaemia: a meta-analysis

Doxani, C.; Voulgarelis, M.; Zintzaras, E. (2013)

Data from 30 pharmacogenomic studies that investigated MDR1 mRNA expression or gene variants (C3435T, G2677TA, C1236T) and response to therapy in acute myeloid leukaemia (AML) were synthesized. Anthracycline-based regimens ...

Network Analysis of Randomized Controlled Trials in Multiple Sclerosis

Zintzaras, E.; Doxani, C.; Mprotsis, T.; Schmid, C. H.; Hadjigeorgiou, G. M. (2012)

Background: The optimal treatment of multiple sclerosis (MS) is not yet well-defined. Objective: To estimate the relative effectiveness of treatments in MS, we performed a network of multiple-treatments meta-analysis of ...

A network meta-analysis of randomized controlled trials for comparing the effectiveness and safety profile of treatments with marketing authorization for relapsing multiple sclerosis

Hadjigeorgiou, G. M.; Doxani, C.; Miligkos, M.; Ziakas, P.; Bakalos, G.; Papadimitriou, D.; Mprotsis, T.; Grigoriadis, N.; Zintzaras, E. (2013)

What is known and objectiveThe relative effectiveness and safety profile of the treatments with marketing authorization for relapsing multiple sclerosis (MS) are not well known because randomized controlled trials with ...

Polymorphisms of the endothelial nitric oxide synthase (NOS3) gene in preeclampsia: a candidate-gene association study

Zdoukopoulos, N.; Doxani, C.; Messinis, I. E.; Stefanidis, I.; Zintzaras, E. (2011)

Background: The endothelial nitric oxide synthase gene (NOS3) has been proposed as a candidate gene for preeclampsia. However, studies so far have produced conflicting results. This study examines the specific role of ...

Polymorphisms of the endothelial nitric oxide synthase gene in breast cancer: a genetic association study and meta-analysis

Zintzaras, E.; Grammatikou, M.; Kitsios, G. D.; Doxani, C.; Zdoukopoulos, N.; Papandreou, C. (2010)

The endothelial nitric oxide synthase gene (NOS3) has been proposed as a candidate gene for breast cancer (BC), however, the specific role of variants and haplotypes has not been clarified. We examined the association of ...

Synopsis and meta-analysis of genetic association studies in osteoporosis for the focal adhesion family genes: the CUMAGAS-OSTEOporosis information system

Zintzaras, E.; Doxani, C.; Koufakis, T.; Kastanis, A.; Rodopoulou, P.; Karachalios, T. (2011)

Background: Focal adhesion (FA) family genes have been studied as candidate genes for osteoporosis, but the results of genetic association studies (GASs) are controversial. To clarify these data, a systematic assessment ...

Variants of the MTHFR gene and susceptibility to acute lymphoblastic leukemia in children: A synthesis of genetic association studies

Zintzaras, E.; Doxani, C.; Rodopoulou, P.; Bakalos, G.; Ziogas, D. C.; Ziakas, P.; Voulgarelis, M. (2012)

Background: Acute lymphoblastic leukemia (ALL) is a complex disease with genetic background. The genetic association studies (GAS) that investigated the association between ALL and the MTHFR C677T and A1298C gene variants ...