Browsing by Subject "BIOMARKERS"

Abnormal serum concentrations of proteins in Parkinson's disease

Goldknopf, I. L.; Bryson, J. K.; Strelets, I.; Quintero, S.; Sheta, E. A.; Mosqueda, M.; Park, H. R.; Appel, S. H.; Shill, H.; Sabbagh, M.; Chase, B.; Kaldjian, E.; Markopoulou, K. (2009)

Blood serum was used to identify protein biomarkers for diagnosis of Parkinson's disease (PD) using analytically validated quantitative 2D-gel electrophoresis, and single variable and multivariate statistics. Using banked ...

Assessment of Eccentric Exercise-Induced Oxidative Stress Using Oxidation-Reduction Potential Markers

Stagos, D.; Goutzourelas, N.; Ntontou, A. M.; Kafantaris, I.; Deli, C. K.; Poulios, A.; Jamurtas, A. Z.; Bar-Or, D.; Kouretas, D. (2015)

The aim of the present study was to investigate the use of static (sORP) and capacity ORP (cORP) oxidation-reduction potential markers as measured by the RedoxSYS Diagnostic System in plasma, for assessing eccentric ...

Assessment of Oxidative Stress in Septic and Obese Patients Using Markers of Oxidation-reduction Potential

Spanidis, Y.; Goutzourelas, N.; Stagos, D.; Kolyva, A. S.; Gogos, C. A.; Bar-Or, D.; Kouretas, D. (2015)

Background/ Aim: The novel static (sORP) and capacity (cORP) oxidation-reduction potential markers were examined for assessing oxidative stress in plasma of patients with sepsis. Moreover, the possible effect of obesity-induced ...

The effect of exercise-induced hypoxemia on blood redox status in well-trained rowers

Kyparos, A.; Riganas, C.; Nikolaidis, M. G.; Sampanis, M.; Koskolou, M. D.; Grivas, G. V.; Kouretas, D.; Vrabas, I. S. (2012)

Exercise-induced arterial hypoxemia (EIAH), characterized by decline in arterial oxyhemoglobin saturation (SaO(2)), is a common phenomenon in endurance athletes. Acute intensive exercise is associated with the generation ...

Evaluation of Current Prognostic and Predictive Markers in Breast Cancer: A Validation Study of Tissue Microarrays

Batistatou, A.; Televantou, D.; Bobos, M.; Eleftheraki, A. G.; Kouvaras, E.; Chrisafi, S.; Koukoulis, G. K.; Malamou-Mitsi, V.; Fountzilas, G. (2013)

Background: Tissue microarrays (TMAs) are an attractive alternative to analysis of whole sections (WS). For breast carcinomas, the recent recommendations for cut-offs (i.e. Ki67, H-score) have necessitated the re-evaluation ...

Evaluation of Neutrophil Gelatinase-associated Lipocalin, Interleukin-18, and Cystatin C as Molecular Markers Before and After Unilateral Shock Wave Lithotripsy

Kardakos, I. S.; Volanis, D. I.; Kalikaki, A.; Tzortzis, V. P.; Serafetinides, E. N.; Melekos, M. D.; Delakas, D. S. (2014)

OBJECTIVE To investigate the impact of shock wave lithotripsy (SWL) on renal tissues using neutrophil gelatinase-associated lipocalin (NGAL), cystatin C, and interleukin 18 (IL-18) levels in serum and urine and to examine ...

HOW CAN BIOINFORMATICS AND TOXICOGENOMICS ASSIST THE NEXT GENERATION OF RESEARCH ON PHYSICAL EXERCISE AND ATHLETIC PERFORMANCE

Kerksick, C. M.; Tsatsakis, A. M.; Hayes, A. W.; Kafantaris, I.; Kouretas, D. (2015)

The past 2-3 decades have seen an explosion in analytical areas related to "omic" technologies. These advancements have reached a point where their application can be and are being used as a part of exercise physiology and ...

Ileal InflammationMay Trigger the Development of GP2-Specific Pancreatic Autoantibodies in Patients with Crohn's Disease

Pavlidis, P.; Romanidou, O.; Roggenbuck, D.; Mytilinaiou, M. G.; Al-Sulttan, F.; Liaskos, C.; Smyk, D. S.; Koutsoumpas, A. L.; Rigopoulou, E. I.; Conrad, K.; Forbes, A.; Bogdanos, D. P. (2012)

Why zymogen glycoprotein 2 (GP2), the Crohn's disease (CD)-specific pancreatic autoantigen, is the major target of humoral autoimmunity in inflammatory bowel diseases (IBD) is uknown. Recent evidence demonstrates that GP2 ...

Passive smoking reduces and vitamin C increases exercise-induced oxidative stress: Does this make passive smoking an anti-oxidant and vitamin C a pro-oxidant stimulus?

Theodorou, A. A.; Paschalis, V.; Kyparos, A.; Panayiotou, G.; Nikolaidis, M. G. (2014)

The current interpretative framework states that, for a certain experimental treatment (usually a chemical substance) to be classified as "anti-oxidant", it must possess the property of reducing (or even nullifying) ...

Prognostic value of C-reactive protein in parapneumonic effusions

Skouras, V.; Boultadakis, E.; Nikoulis, D.; Polychronopoulos, V.; Daniil, Z.; Kalomenidis, I.; Gourgoulianis, K. I. (2012)

Background and objective: Parapneumonic effusions (PPE) that require drainage are referred to as complicated parapneumonic effusions (CPPE). Following resolution of these effusions, residual pleural thickening (RPT) may ...

Secondhand smoke exposure induces acutely airway acidification and oxidative stress

Kostikas, K.; Minas, M.; Nikolaou, E.; Papaioannou, A. I.; Liakos, P.; Gougoura, S.; Gourgoulianis, K. I.; Dinas, P. C.; Metsios, G. S.; Jamurtas, A. Z.; Flouris, A. D.; Koutedakis, Y. (2013)

Previous studies have shown that secondhand smoke induces lung function impairment and increases proinflammatory cytokines. The aim of the present study was to evaluate the acute effects of secondhand smoke on airway ...

Serotonin and Neuron-specific Enolase: Serum Acute and Mid-term Levels and their Association With Posttraumatic Depression

Wozniak, G.; Georgoulias, P.; Iliadis, C.; Valotasiou, V.; Papadopoulos, G.; Bagiatis, V.; Tsougos, I.; Paterakis, K. N.; Fountas, K. N. (2010)

Objectives: To investigate the association between serotonin (SER), cholesterol, and neuron-specific enolase (NSE) serum levels with depression after traumatic brain injury (TBI). Materials and Methods: Seventy-four patients ...