Πλοήγηση ανά Θέμα "1 (2' amino 2' deoxy beta dextro glucopyranosyl) 4 phenyl 1,2,3 triazole"

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Nanomolar Inhibitors of Glycogen Phosphorylase Based on β- D -Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study

Bokor E., Kyriakis E., Solovou T.G.A., Koppány C., Kantsadi A.L., Szabó K.E., Szakács A., Stravodimos G.A., Docsa T., Skamnaki V.T., Zographos S.E., Gergely P., Leonidas D.D., Somsák L. (2017)

Aryl substituted 1-(β-d-glucosaminyl)-1,2,3-triazoles as well as C-β-d-glucosaminyl 1,2,4-triazoles and imidazoles were synthesized and tested as inhibitors against muscle and liver isoforms of glycogen phosphorylase (GP). ...