Listar por tema "renin angiotensin aldosterone system"

COVID-19 immunopathology and the central nervous system: Implication for multiple sclerosis and other autoimmune diseases with associated demyelination

Boziki M.K., Mentis A.-F.A., Shumilina M., Makshakov G., Evdoshenko E., Grigoriadis N. (2020)

In the frame of the coronavirus disease 2019 (COVID-19) pandemic, recent reports on SARS-CoV-2 potential neuroinvasion placed neurologists on increased alertness in order to assess early neurological manifestations and ...

Dietary antioxidant supplements and uric acid in chronic kidney disease: A review

Roumeliotis S., Roumeliotis A., Dounousi E., Eleftheriadis T., Liakopoulos V. (2019)

Increased serum levels of uric acid have been associated with the onset and development of chronic kidney disease (CKD), cardiovascular disease, and mortality, through several molecular pathogenetic mechanisms, such as ...

Encapsulating peritoneal sclerosis: Pathophysiology and current treatment options

Jagirdar R.M., Bozikas A., Zarogiannis S.G., Bartosova M., Schmitt C.P., Liakopoulos V. (2019)

Encapsulating peritoneal sclerosis (EPS) is a life-threatening complication of long-term peritoneal dialysis (PD), which may even occur after patients have switched to hemodialysis (HD) or undergone kidney transplantation. ...

Evidence for Cardiorenal Protection with SGLT-2 Inhibitors and GLP-1 Receptor Agonists in Patients with Diabetic Kidney Disease

Georgianos P.I., Vaios V., Roumeliotis S., Leivaditis K., Eleftheriadis T., Liakopoulos V. (2022)

For almost two decades, the management of patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) was based on the optimal glycemic and blood pressure control as well as on the adequate blockade of ...

The genetic map of diabetic nephropathy: Evidence from a systematic review and meta-analysis of genetic association studies

Tziastoudi M., Stefanidis I., Zintzaras E. (2020)

Despite the extensive efforts of scientists, the genetic background of diabetic nephropathy (DN) has not yet been clarified. To elucidate the genetic variants that predispose to the development of DN, we conducted a ...

Glycaemic control in heart failure: a PARADIGM shift for patients with concomitant diabetes?

Giamouzis G., Butler J. (2017)

[No abstract available]

Hypertension in chronic kidney disease: Novel insights

Duni A., Dounousi E., Pavlakou P., Eleftheriadis T., Liakopoulos V. (2020)

Management of arterial hypertension in patients with chronic kidney disease (CKD) remains a major challenge due to its high prevalence and associations with cardiovascular disease (CVD) and CKD progression. Several clinical ...

Impact of renin–angiotensin–aldosterone system polymorphisms on myocardial perfusion: Correlations with myocardial single photon emission computed tomography-derived parameters

Angelidis G., Samara M., Papathanassiou M., Satra M., Valotassiou V., Tsougos I., Psimadas D., Tzavara C., Alexiou S., Koutsikos J., Demakopoulos N., Giamouzis G., Triposkiadis F., Skoularigis J., Kollia P., Georgoulias P. (2019)

Background: Renin–angiotensin–aldosterone system (RAAS) has an important role in atherosclerosis. We investigated the effects of six RAAS gene polymorphisms on myocardial perfusion. Methods and Results: We examined 810 ...

The importance of managing diabetes correctly to prevent heart failure

Triposkiadis, F.; Giamouzis, G.; Butler, J. (2011)

Increased mortality among hypertensive COVID-19 patients: Pay a closer look on diuretics in mechanically ventilated patients

Tsolaki V., Zakynthinos G.E., Mantzarlis K., Makris D. (2020)

[No abstract available]

Management of blood pressure and heart rate in chronic kidney disease

Kaltsatou A. (2017)

Background: Hypertension is considered a major health problem in patients with chronic kidney disease (CKD) as approximately 80-85% of CKD patients’ suffer from hypertension in the United States. Hypertension is the second ...

Molecular Mechanisms of Peritoneal Membrane Pathophysiology

Zarogiannis S.G., Schmitt C.P. (2022)

[No abstract available]

Novel Therapeutic Strategies for Cardiorenal Protection in Patients with Type 2 Diabetes and Chronic Kidney Disease

Georgianos P.I., Roumeliotis S., Eleftheriadis T., Liakopoulos V. (2022)

Type 2 diabetes mellitus (T2DM) is the leading cause of end-stage kidney disease (ESKD) worldwide [1]. The development of chronic kidney disease (CKD) in patients with T2DM sub-stantially increases their risk for cardiovascular ...

Red blood cell distribution width in elderly hospitalized patients with cardiovascular disease

Xanthopoulos A., Tryposkiadis K., Dimos A., Bourazana A., Zagouras A., Iakovis N., Papamichalis M., Giamouzis G., Vassilopoulos G., Skoularigis J., Triposkiadis F. (2021)

BACKGROUND Red blood cell distribution width (RDW) is elevated in patients with cardiovascular disease (CVD). AIM To determine RDW values and impact of CV and non-CV coexisting morbidities in elderly patients hospitalized ...

Renin-angiotensin system single nucleotide polymorphisms are associated with bladder cancer risk

Samara M., Papathanassiou M., Farmakioti I., Anagnostou M., Satra M., Mitrakas L., Anastasiou D., Chasiotis G., Christopoulos A., Anagnostou A., Christodoulou A., Daponte A., Ioannou M., Koukoulis G., Tzortzis V., Vlachostergios P.J. (2021)

The renin-angiotensin system (RAS), besides being a major regulator of blood pressure, is also involved in tumor angiogenesis. Emerging evidence suggests a correlation between the use of pharmacologic RAS inhibitors and a ...

Renin-angiotensin-system inhibition in the context of corona virus disease-19: experimental evidence, observational studies, and clinical implications

Triposkiadis F., Starling R.C., Xanthopoulos A., Butler J., Boudoulas H. (2021)

Coronavirus disease 2019 (COVID-19) is due to severe acute respiratory syndrome coronavirus (SARS-CoV)-2 which binds and enters the host cells through the angiotensin-converting enzyme (ACE)2. While the potential for benefit ...

The role of genetic polymorphisms of the Renin-Angiotensin System in renal diseases: A meta-analysis

Braliou, G. G.; Grigoriadou, A. M. G.; Kontou, P. I.; Bagos, P. G. (2014)

Renal failure has a complex phenotype resulting from an underlying kidney disease as well as environmental and genetic factors. In the present study we performed a systematic review and meta-analyses to evaluate the ...