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Parcourir par sujet "modifier gene"

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    • Gene variants of adhesion molecules act as modifiers of disease severity in MS 

      Dardiotis E., Panayiotou E., Provatas A., Christodoulou K., Hadjisavvas A., Antoniades A., Lourbopoulos A., Pantzaris M., Grigoriadis N., Hadjigeorgiou G.M., Kyriakides T. (2017)
      Objective: To assess the potential effect of variants in genes encoding molecules that are implicated in leukocyte trafficking into the CNS on the clinical phenotype of multiple sclerosis (MS). Methods: A total of 389 Greek ...

    • New molecular diagnostic trends and biomarkers for amyotrophic lateral sclerosis 

      Pampalakis G., Mitropoulos K., Xeromerisiou G., Dardiotis E., Deretzi G., Anagnostouli M., Katsila T., Rentzos M., Patrinos G.P. (2019)
      Amyotrophic lateral sclerosis (ALS) is a rare and fatal neurodegenerative disorder. Two forms are recognized, familial (FALS) that accounts for 5–10% of ALS cases, and sporadic (SALS) that accounts for the rest. Early ...