Auflistung Nach Schlagwort "microsatellite instability"

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Detection of microsatellite instability in sporadic cardiac myxomas

Sourvinos, G.; Parissis, J.; Sotsiou, F.; Arvanitis, D. L.; Spandidos, D. A. (1999)

Objective: Microsatellite instability (MIN) is an early event in DNA repair-deficient associated diseases and reflects an elevated mutation rate in the genome of neoplastic cells. Sporadic cardiac myxomas are the most ...
Immunotherapy Efficacy in the Initial Lines of Treatment in Advanced Upper Gastrointestinal Malignancies: A Systematic Review of the Literature

Kamposioras K., Ntellas P., Nikolaou M., Germetaki T., Gazouli I., Dadouli K., Zarkavelis G., Amylidi A.-L., Tolia M., Mauri D. (2021)

Background: The therapeutic role of immune checkpoint inhibitors (ICIs) has represented the cutting edge of clinical research in upper gastrointestinal (GI) malignancies, with these agents now included in the armamentarium ...
Microsatellite instability and loss of heterozygosity at the MEN1 locus in lung carcinoid tumors: A novel approach using real-time PCR with melting curve analysis in histopathologic material

Vageli, D.; Daniil, Z.; Dahabreh, J.; Karagianni, E.; Liloglou, T.; Koukoulis, G.; Gourgoulianis, K. (2006)

The possible causes and genetic mechanisms of pulmonary carcinoid tumor development are unclear. In this study, we examined genetic alterations at the MEN1 locus in archival material from 15 pulmonary carcinoids. We employed, ...