Browsing by Subject "malignant pleura effusion"
Now showing items 1-12 of 12
-
Discrimination of exudative pleural effusions based on pleural adenosine deaminase (Ada)-c-reactive protein (crp) levels, and their combination: An observational prospective study
(2021)(1) Background: Malignant (MPE), parapneumonic (PPE) and tuberculous (TPE) pleural effusions constitute common causes of pleurisy. Discriminating among them is usually challenging. C-reactive protein (CRP) and adenosine ... -
HΜGB1/sRAGE levels differ significantly between transudates and exudates
(2021)High mobility group box 1(HMGB1) protein operates as an alarmin with multiple roles in immunity and cell homeostasis. It is highly expressed in epithelial barrier sites and acts via the binding to the receptor for advanced ... -
Mortality Among Hospitalized Patients With Pleural Effusions. A Multicenter, Observational, Prospective Study
(2022)Background: Data regarding the prognostic significance of pleural effusion (PE) are scarce. Objective: Explore the impact of PE on mortality among hospitalized patients. Methods: Multicenter prospective observational study. ... -
Pleural effusion levels of dj-1 are increased in elderly lung cancer patients with malignant pleural effusions
(2015)Objectives: DJ-1 is a multifunctional protein implicated in redox dependent cell fate decisions. The aim of ourstudy was to determine the pleural fluid (PF) levels of DJ-1 in malignant pleural effusions (MPEs) secondary ... -
Pleural effusion osmolality correlation with pH and glucose level of pleural fluid and its effects on the pleural membrane permeability
(2021)Background and aim: Pleural effusions (PE) are a common clinical entity resulting from pathologies that affect the pleural space such as congestive heart failure, malignancy and pneumonia. The osmolality of the pleural ... -
A potential role for VEGF in the diagnostic approach of pleural effusions
(2016)Background: Vascular endothelial growth factor (VEGF) may play a role in pleural fluid formation, as it represents a potent inducer of capillary permeability. We aimed to investigate the diagnostic utility of VEGF levels ... -
Repeatability of pleural adenosine deaminase measurements in diagnostic evaluation of pleural effusions
(2018)Background: A follow-up thoracentesis is proposed in suspected atypical tuberculosis cases. The study aimed to define the variability of pleural ADA values across repeated thoracenteses in different types of pleural effusions ... -
The role of nitric oxide in pleural disease
(2021)Nitric oxide (NO) regulates various physiological and pathophysiological functions in the lungs. However, there is much less information about the effects of NO in the pleura. The present review aimed to explore the available ... -
Sestrin-2 is significantly increased in malignant pleural effusions due to lung cancer and is potentially secreted by pleural mesothelial cells
(2016)Objectives: Sestrin-2 (Sesn2) belongs to a family of highly conserved antioxidant proteins that were discovered as p53-inducible proteins and inhibits cell growth and proliferation. Our aim was to assess the levels of Sesn2 ... -
Systematic review and meta-analysis of vascular endothelial growth factor as a biomarker for malignant pleural effusions
(2016)Conventional methods may fail to identify the cause of pleural effusion (PE), thus establishing reliable biomarkers is deemed necessary. This study aimed at examining the role of vascular endothelial growth factor (VEGF) ... -
Talc pleurodesis in malignant pleural effusion: a systematic review and meta-analysis
(2021)Objective: Malignant pleural effusion is a severe and common complication in patients with primary or metastatic malignancies of the pleura. Although talc pleurodesis is widely used for managing malignant pleural effusions, ... -
Toward fully exploiting the therapeutic potential of marketed pharmaceuticals: The use of octreotide and chloroquine in oncology
(2019)Pleiotropy in biological systems and their targeting allows many pharmaceuticals to be used for multiple therapeutic purposes. Fully exploiting the therapeutic properties of drugs that are already marketed would be highly ...