• IL-33/ST2 axis in organ fibrosis 

      Kotsiou O.S., Gourgoulianis K.I., Zarogiannis S.G. (2018)
      Interleukin 33 (IL-33) is highly expressed in barrier sites, acting via the suppression of tumorigenicity 2 receptor (ST2). IL-33/ST2 axis has long been known to play a pivotal role in immunity and cell homeostasis by ...
    • Nephrotoxicity in rabbits after long-term nandrolone decanoate administration 

      Tsitsimpikou C., Vasilaki F., Tsarouhas K., Fragkiadaki P., Tzardi M., Goutzourelas N., Nepka C., Kalogeraki A., Heretis I., Epitropaki Z., Kouretas D., Tsatsakis A.M. (2016)
      Among the various side effects of supra-physiological dose of anabolic androgenic steroids that are described, renal toxicity remains the least evaluated. The present study provides evidence that long-term administration ...
    • The role of Dickkopf-1 in joint remodeling and fibrosis: A link connecting spondyloarthropathies and scleroderma? 

      Klavdianou K., Liossis S.-N., Sakkas L., Daoussis D. (2017)
      Background Dickkopf-1 (Dkk-1) is a soluble inhibitor of the canonical Wnt pathway, which plays critical roles in embryonic development. Evidence suggests that this molecule regulates several aspects of both bone biology ...
    • Toll-like receptors and their role in renal pathologies 

      Eleftheriadis, T.; Pissas, G.; Liakopoulos, V.; Stefanidis, I.; Lawson, B. R. (2012)
      Toll-like receptors (TLRs) are the first identified and best studied family of pattern recognition receptors. Expressed in immunocytes, TLRs initiate innate immune responses and concurrently shape the subsequent adaptive ...