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Browsing by Subject "interleukin 35"

Now showing items 1-3 of 3

    • IL-35: a new immunomodulator in autoimmune rheumatic diseases 

      Sakkas L.I., Mavropoulos A., Perricone C., Bogdanos D.P. (2018)
      IL-35 is a relatively new cytokine that emerges as an important immunomodulator. IL-35 belongs to IL-12 cytokine family that includes IL-12, IL-23, IL-27, and IL-35. These cytokines are heterodimers that share subunits and ...

    • On the immunoregulatory role of statins in multiple sclerosis: the effects on Th17 cells 

      Ntolkeras G., Barba C., Mavropoulos A., Vasileiadis G.K., Dardiotis E., Sakkas L.I., Hadjigeorgiou G., Bogdanos D.P. (2019)
      Statins, the cholesterol-lowering drugs, also possess immunomodulatory properties, affecting among others T cell activation and differentiation, antigen presentation, and regulatory T cell (Tregs) maintenance and ...

    • Regulatory B and T lymphocytes in multiple sclerosis: friends or foes? 

      Vasileiadis G.K., Dardiotis E., Mavropoulos A., Tsouris Z., Tsimourtou V., Bogdanos D.P., Sakkas L.I., Hadjigeorgiou G.M. (2018)
      Current clinical experience with immunomodulatory agents and monoclonal antibodies in principle has established the benefit of depleting lymphocytic populations in relapsing–remitting multiple sclerosis (RRMS). B and T ...