Auflistung Nach Schlagwort "gemcitabine"

Acute leriche syndrome in pancreatic adenocarcinoma: A case report

Mosa E., Manouvelou S., Tolia M., Tsoukalas N., Ardavanis A., Stasinopoulou M., Kyrgias G., Tavernaraki A. (2020)

Introduction: Coexistance of pancreatic carcinoma and Leriche syndrome is an extremely rare pathological condition. Leriche syndrome is defined as occlusion of the distal aorta at the bifurcation into the common iliac ...

Advanced Non-linear Mathematical Model for the Prediction of the Activity of a Putative Anticancer Agent in Human-to-mouse Cancer Xenografts

Liliopoulos S.G., Stavrakakis G.S., Dimas K.S. (2020)

Background/Aim: Mathematical models have long been considered as important tools in cancer biology and therapy. Herein, we present an advanced non-linear mathematical model that can predict accurately the effect of an ...

Assessment of the efficacy and clinical utility of different circulating tumor cell (CTC) detection assays in patients with chemotherapy-naïve advanced or metastatic non-small cell lung cancer (NSCLC)

Papadaki M.A., Messaritakis I., Fiste O., Souglakos J., Politaki E., Kotsakis A., Georgoulias V., Mavroudis D., Agelaki S. (2021)

We herein investigated the detection frequency and clinical relevance of circulating tumor cells (CTCs) in chemotherapy-naïve stage IIIB/IV non-small cell lung cancer (NSCLC), by using the CellSearch and real-time CEACAM5mRNA ...

A meta-analysis evaluating the role of high-intensity focused ultrasound (HIFU) as a fourth treatment modality for patients with locally advanced pancreatic cancer

Fergadi M.P., Magouliotis D.E., Rountas C., Vlychou M., Athanasiou T., Symeonidis D., Pappa P.A., Zacharoulis D. (2022)

Background: This study aimed to evaluate the outcomes of high-intensity focused ultrasound (HIFU) on patients with advanced pancreatic cancer. Methods: A literature search was performed in PubMed, Scopus and Cochrane ...

Myeloid-derived suppressor cells: Major figures that shape the immunosuppressive and angiogenic network in cancer

Vetsika E.-K., Koukos A., Kotsakis A. (2019)

Myeloid-derived suppressor cells (MDSCs) constitute a vast population of immature myeloid cells implicated in various conditions. Most notably, their role in cancer is of great complexity. They exert immunosuppressive ...

The proteasome as a target for cancer treatment: Focus on bortezomib

Papandreou, C. N. (2005)

Targeted degradation of key regulatory proteins is an essential element of cell-cycle control. The proteasome plays a pivotal role in the degradation of such proteins and has, therefore, become an important therapeutic ...

Self-Healing pH- and Enzyme Stimuli-Responsive Hydrogels for Targeted Delivery of Gemcitabine to Treat Pancreatic Cancer

Bilalis P., Skoulas D., Karatzas A., Marakis J., Stamogiannos A., Tsimblouli C., Sereti E., Stratikos E., Dimas K., Vlassopoulos D., Iatrou H. (2018)

A novel, multifunctional hydrogel that exhibits a unique set of properties for the effective treatment of pancreatic cancer (PC) is presented. The material is composed of a pentablock terpolypeptide of the type ...

Silencing of caveolin-1 in fibroblasts as opposed to epithelial tumor cells results in increased tumor growth rate and chemoresistance in a human pancreatic cancer model

Kamposioras K., Tsimplouli C., Verbeke C., Anthoney A., Daoukopoulou A., Papandreou C.N., Sakellaridis N., Vassilopoulos G., Potamianos S.P., Liakouli V., Migneco G., Galdo F.D.E.L., Dimas K. (2019)

Caveolin-1 (Cav-1) expression has been shown to be associated with tumor growth and resistance to chemotherapy in pancreatic cancer. The primary aim of this study was to explore the significance of Cav-1 expression in ...

Treatment of lung cancer

Rapti, A.; Kerenidi, T.; Zarogoulidis, K. (2012)