Tutto DSpace

Sfoglia per Soggetto "drug distribution"

Items 1-6 di 6

    • Focus on the use of resveratrol as an adjuvant in glioblastoma therapy 

      Dionigi L., Ragonese F., Monarca L., Covino S., de Luca A., Iannitti R.G., Bastioli F., Moulas A.N., Allegretti M., Fioretti B. (2020)
      Glioblastoma (GB) represents the most common and malignant form of glioma cancer. The Gold Standard in Glioblastoma is neurosurgical tumor removal and radiotherapy treatment in concomitant with temo-zolomide (TMZ). ...

    • High intratumoural accumulation of stealth® liposomal doxorubicin (Caelyx®) in glioblastomas and in metastatic brain tumours 

      Koukourakis, M. I.; Koukouraki, S.; Fezoulidis, I.; Kelekis, N.; Kyrias, G.; Archimandritis, S.; Karkavitsas, N. (2000)
      The blood-brain barrier is a major obstacle for the chemotherapeutic drugs to effectively reach primary or secondary brain tumours, Stealth® liposomal drugs are highly accumulated in tumoural tissues. In the present study ...

    • Nanosystems for the encapsulation of natural products: The case of chitosan biopolymer as a matrix 

      Detsi A., Kavetsou E., Kostopoulou I., Pitterou I., Pontillo A.R.N., Tzani A., Christodoulou P., Siliachli A., Zoumpoulakis P. (2020)
      Chitosan is a cationic natural polysaccharide, which has emerged as an increasingly interesting biomaterialover the past few years. It constitutes a novel perspective in drug delivery systems and nanocarriers’ formulations ...

    • Pharmacokinetic disposition of amiodarone when given with an intralipid rescue strategy 

      Avedissian S.N., Pham M., Joshi M.D., Scheetz M.H., Salamatipour A., Panickar J.M., Hlukhenka K., Miglis C., Chalkias A., Xanthos T. (2021)
      While the antiarrhythmic drug amiodarone is commonly used in clinical practice, it has a narrow therapeutic index that can lead to acute overdose. One proposed method to deal with this toxicity is lipid emulsion therapy, ...

    • The Role of Ketamine in Object Recognition Memory in Rodents 

      Pitsikas N. (2018)
      The object recognition test (ORT) was developed to assess the role of brain structures and neurochemical systems in memory processes in rodents, mainly rats and mice. It is based on spontaneous exploratory behaviour; hence ...

    • Upadacitinib tartrate in rheumatoid arthritis 

      Stamatis P., Bogdanos D.P., Sakkas L.I. (2020)
      does not achieve low disease activity or remission despite the use of conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) and/or biological DMARDs (bDMARDs). The Janus kinase (JAK) inhibitors are the ...