Browsing by Subject "drug conformation"

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Phytogenic polyphenols as glycogen phosphorylase inhibitors: The potential of triterpenes and flavonoids for glycaemic control in type 2 diabetes

Stravodimos G.A., Chetter B.A., Kyriakis E., Kantsadi A.L., Chatzileontiadou D.S.M., Skamnaki V.T., Kato A., Hayes J.M., Leonidas D.D. (2017)

Glycogen phosphorylase (GP) is a validated pharmaceutical target for the development of antihyperglycaemic agents. Phytogenic polyphenols, mainly flavonoids and pentacyclic triterpenes, have been found to be potent inhibitors ...