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Sfoglia per Soggetto "daunorubicin"

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    • Cardiotoxicity of Chemical Substances: An Emerging Hazard Class 

      Georgiadis N., Tsarouhas K., Dorne J.-L.C.M., Kass G.E.N., Laspa P., Toutouzas K., Koulaouzidou E.A., Kouretas D., Tsitsimpikou C. (2022)
      (1) Background: Human health risks and hazards from chemical substances are well regulated internationally. However, cardiotoxicity, is not defined as a stand-alone hazard and therefore there are no defined criteria for ...

    • The proteasome as a target for cancer treatment: Focus on bortezomib 

      Papandreou, C. N. (2005)
      Targeted degradation of key regulatory proteins is an essential element of cell-cycle control. The proteasome plays a pivotal role in the degradation of such proteins and has, therefore, become an important therapeutic ...

    • What is considered cardiotoxicity of anthracyclines in animal studies 

      Georgiadis N., Tsarouhas K., Rezaee R., Nepka H., Kass G.E.N., Dorne J.-L.C.M., Stagkos D., Toutouzas K., Spandidos D.A., Kouretas D., Tsitsimpikou C. (2020)
      Anthracyclines are commonly used anticancer drugs with well.known and extensively studied cardiotoxic effects in humans. In the clinical setting guidelines for assessing cardiotoxicity are well.established with important ...