Πλοήγηση ανά Θέμα "colorectal cancer"
Αποτελέσματα 1-20 από 23
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Alterations of microRNAs in solid cancers and their prognostic value
(2010)MicroRNAs (miRNAs) are evolutionarily conserved, naturally abundant, small, regulatory non-coding RNAs that inhibit gene expression at the post-transcriptional level in a sequence-specific manner. Each miRNA represses the ... -
Association of Syndecan-1 with Angiogenesis-related Markers, Extracellular Matrix Components, and Clinicopathological Features in Colorectal Carcinoma
(2012)Syndecan-1 is a transmembrane heparansulfate proteoglycan, which regulates cell proliferation, migration, angiogenesis, cell-to-cell and cell-to-extracellular matrix adhesion and may influence malignant cell behavior. We ... -
Bax protein expression in colorectal cancer: Association with p53, bcl-2 and patterns of relapse
(2001)This study evaluated the frequency and the prognostic significance of bax, bcl-2 and p53 proteins in stage B and C adenocarcinomas of the colon and rectum. Paraffin-embedded specimens from 268 patients with colorectal ... -
Bisphosphonate use and risk of colorectal cancer: a systematic review and meta-analysis
(2013)AimA growing body of evidence suggests that bisphosphonates may have chemopreventive potential against colorectal cancer. Our aim was to examine this association through a meta-analysis of observational studies. MethodsA ... -
Bootstrap-based testing approaches for the assessment of the diagnostic accuracy of biomarkers subject to a limit of detection
(2019)Assessment of the diagnostic accuracy of biomarkers through receiver operating characteristic curve analysis frequently involves a limit of detection imposed by the laboratory analytical system precision. As a consequence, ... -
Cancer-associated stroke: Pathophysiology, detection and management (Review)
(2019)Numerous types of cancer have been shown to be associated with either ischemic or hemorrhagic stroke. In this review, the epidemiology and pathophysiology of stroke in cancer patients is discussed, while providing vital ... -
Exercise, supportive group therapy, and mood profile of Greek cancer patients: intervention effect and related comparisons
(2018)Purpose: The purpose of this study was to examine the effect of exercise program and a group psychotherapy program on mood profile of Greek cancer patients as well as to make the necessary comparisons. Methods: The sample ... -
Exploring the potential of mucin 13 (MUC13) as a biomarker for carcinomas and other diseases
(2018)Mucin 13 (MUC13) is a cell surface glycoprotein aberrantly expressed in a variety of epithelial carcinomas. Thus far, the role of MUC13 in various diseases remains elusive. To the best of our knowledge, this is the first ... -
Expression profile of the GA733 gene family in colorectal cancer: Correlation with clinicopathological parameters
(2015)GA733-1/-2/-3 genes have been detected in various types of cancer, although their role has not been fully clarified. GA733-2 and GA733-1 have been correlated with lymph node metastases in laryngeal cancer and liver metastases, ... -
Helicobacter pylori Infection and Gastroesophageal Reflux Disease–Barrett’s Esophagus–Esophageal Adenocarcinoma Sequence
(2018)[No abstract available] -
How can we effectively address the paraneoplastic dermatomyositis: Diagnosis, risk factors and treatment options
(2017)Purpose: Dermatomyositis (DM) represents an auto-immune inflammatory myopathy. In this review, we analyzed the incidence of DM as a clinical manifestation highlighting the peculiar clinical and treatment characteristics ... -
Identification of neoplasm-specific signatures of miRNA interactions by employing a systems biology approach
(2022)MicroRNAs represent major regulatory components of the disease epigenome and they constitute powerful biomarkers for the accurate diagnosis and prognosis of various diseases, including cancers. The advent of high-throughput ... -
Impact of reactive oxygen species generation on Helicobacter pylori-related extragastric diseases: a hypothesis
(2017)Helicobacter pylori (H. pylori) induces reactive oxygen species (ROS) production that contribute to pathogenesis of a variety of H. pylori-related gastric diseases, as shown in animal and human studies. Helicobacter pylori ... -
Intestinal microbiota and colorectal cancer: A new aspect of research
(2018)Colon holds a complex microbial community, which is crucial for maintaining homeostasis and regulating metabolic functions, supporting the intestinal barrier and controlling immune responses. Previous studies have supported ... -
Intestinal microbiota in colorectal cancer surgery
(2020)The intestinal microbiota consists of numerous microbial species that collectively interact with the host, playing a crucial role in health and disease. Colorectal cancer is well-known to be related to dysbiotic alterations ... -
Myeloid-derived suppressor cells in prostate cancer: Present knowledge and future perspectives
(2022)Several lines of research are being investigated to better understand mechanisms implicated in response or resistance to immune checkpoint blockade in prostate cancer (PCa). Myeloid-derived suppressor cells (MDSCs) have ... -
Physicians’ experience, practice and education, on genetic testing and genetic counseling: a nationwide survey study in Greece
(2022)Genetic testing has been implemented in clinical practice. However, data on physician’s practices and education related to cancer genetics, risk assessment and clinical management in Greece, is limited. In Greece, genetic ... -
Prognostic significance and therapeutic implications of Caveolin-1 in gastrointestinal tract malignancies
(2022)Caveolin-1 (CAV1) is expressed in several solid tumors both in cancerous cells as well as in tumor stroma and is reported to be related to cancer progression, metastasis, therapy resistance and clinical outcomes. Many ... -
The prognostic significance of the Hedgehog signaling pathway in colorectal cancer
(2016)Despite significant advances in the management of colorectal cancer (CRC) the identification of new prognostic biomarkers continues to be a challenge. Since its initial discovery, the role of the Hedgehog (Hh) signaling ... -
Prognostic significance of tumor genotypes and CD8+ infiltrates in stage I-III colorectal cancer
(2018)Background: We explored the clinical significance of tumor genotypes and immunophenotypes in non-metastatic colorectal cancer (CRC). Methods: In primary tumors (paraffin blocks) from 412 CRC patients treated with adjuvant ...