Sfoglia per Soggetto "TLR4"
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Association of TLR4-T399I Polymorphism with Chronic Obstructive Pulmonary Disease in Smokers
(2009)Tobacco smoking has been considered the most important risk factor for chronic obstructive pulmonary disease (COPD) development. However, not all smokers develop COPD and other environmental and genetic susceptibility ... -
Genetic polymorphisms of innate and adaptive immunity as predictors of outcome in critically ill patients
(2015)Sepsis and septic shock frequently cause the admission or complicate the clinical course of critically ill patients admitted in the intensive care units (ICU). Genetic variations disrupting the immune sensing of infectious ... -
Readressing the Role of Toll-Like Receptor-4 Alleles in Inflammatory Bowel Disease: Colitis, Smoking, and Seroreactivity
(2013)Toll-like receptor (TLR) polymorphisms, and especially TLR-4 Asp299Gly and TLR-4 Thr399Ile, have been linked with Crohn's disease (CD) and to a lesser extent with ulcerative colitis (UC), CD behavior, and compromised ... -
TLR2 and TLR4 polymorphisms in familial Mediterranean fever
(2009)It has been suggested that MEVF mutations offer advantage against infections, including tuberculosis. Bearing in mind the central role of TLR-2 and TLR-4 in the recognition of pathogens, we conducted this study to examine ...