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Browsing by Subject "Sumoylation"

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    • Hypoxia-induced Changes in SUMO Conjugation Affect Transcriptional Regulation under Low Oxygen 

      Chachami G., Stankovic-Valentin N., Karagiota A., Basagianni A., Plessmann U., Urlaub H., Melchior F., Simos G. (2019)
      Hypoxia occurs in pathological conditions, such as cancer, as a result of the imbalance between oxygen supply and consumption by proliferating cells. HIFs are critical molecular mediators of the physiological response to ...

    • The Role of Sumoylation in the Response to Hypoxia: An Overview 

      Filippopoulou C., Simos G., Chachami G. (2020)
      Sumoylation is the covalent attachment of the small ubiquitin-related modifier (SUMO) to a vast variety of proteins in order to modulate their function. Sumoylation has emerged as an important modification with a regulatory ...