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Browsing by Subject "RNA binding protein"

Now showing items 1-2 of 2

    • Cold shock Y-box protein-1 proteolysis autoregulates its transcriptional activities 

      Van Roeyen, C. R. C.; Scurt, F. G.; Brandt, S.; Kuhl, V. A.; Martinkus, S.; Djudjaj, S.; Raffetseder, U.; Royer, H. D.; Stefanidis, I.; Dunn, S. E.; Dooley, S.; Weng, H.; Fischer, T.; Lindquist, J. A.; Mertens, P. R. (2013)
      Background: The Y-box protein-1 (YB-1) fulfills pleiotropic functions relating to gene transcription, mRNA processing, and translation. It remains elusive how YB-1 shuttling into the nuclear and cytoplasmic compartments ...

    • mTORC2 deploys the mRNA binding protein IGF2BP1 to regulate c-MYC expression and promote cell survival 

      Lambrianidou A., Sereti E., Soupsana K., Komini C., Dimas K., Trangas T. (2021)
      mTORC2 promotes cell survival by phosphorylating AKT and enhancing its activity. Inactivation of mTORC2 reduces viability through down-regulation of E2F1 caused by up-regulation of c-MYC. An additional target of mTORC2 is ...